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  1. 30 医学部・医学研究科・保健学研究科
  2. 30b 弘前医学 = Hirosaki Medical Journal
  3. 70巻2-4号

Outcome of concomitant surgical treatment in patients with coronary artery disease and severe aortic stenosis: A single-center study

http://hdl.handle.net/10129/00006959
http://hdl.handle.net/10129/00006959
bf412b5f-3fdc-4f48-9b91-5697aafcfcf4
名前 / ファイル ライセンス アクション
Hirosaki Hirosaki Med J 70-2-4_99 (707.5 kB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2020-03-06
タイトル
タイトル Outcome of concomitant surgical treatment in patients with coronary artery disease and severe aortic stenosis: A single-center study
言語
言語 eng
キーワード
主題Scheme Other
主題 aortic stenosis
キーワード
主題Scheme Other
主題 aortic valve replacement
キーワード
主題Scheme Other
主題 coronary artery disease
キーワード
主題Scheme Other
主題 coronary artery bypass grafting
キーワード
主題Scheme Other
主題 combined operation
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Yu, Zaiqiang

× Yu, Zaiqiang

Yu, Zaiqiang

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Daitoku, Kazuyuki

× Daitoku, Kazuyuki

Daitoku, Kazuyuki

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Yang, Wei

× Yang, Wei

Yang, Wei

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Kondo, Norihiro

× Kondo, Norihiro

Kondo, Norihiro

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Minakawa, Masahito

× Minakawa, Masahito

Minakawa, Masahito

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Fukuda, Ikuo

× Fukuda, Ikuo

Fukuda, Ikuo

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著者所属
値 Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine
抄録
内容記述タイプ Abstract
内容記述 Background: Combined aortic valve replacement( AVR) and coronary artery bypass grafting(ABG)is mostly performed for patients with aortic stenosis( AS) and coronary artery disease( AD).
Objectives: We aim to clarify that combined operation of AVR and CABG with adequate perioperative ardiac protection does not increase operative and postoperative risk.
Methods: A total of 217 patients who underwent AVR for aortic stenosis alone or combined AVR and CABG from 1/2002 to 12/2015 were recruited. The aortic valve alone group (group A) had 164 patients, with an average age of 71.6± 8.1 years. The combined operation group (group C) consisted of 54 patients, with an average age of 73.5±8.5 years. Aortic valve area and pressure gradient showed no significant differences between the two groups. In group C, an average of 2±0.8 vessels had CAD. Cold crystalloid cardioplegia according to left ventricular mass ± a terminal hot shot was used for all patients. Distal graft anastomosis was done after cardiac arrest and cardioplegia (1.5-fold normal) was injected additionally from the graft with severe proximal obstruction of the right coronary artery.
Results: Group C included more patients with diabetes mellitus (DM, 43.4% vs. 26.8%) and low left ventricular ejection fraction( LVEF<50%, 33.96% vs. 16.46%) than group A. On the other hand, the incidence of atrial fibrillation( AF, .77% vs. 13.41%) was significantly less in group C than in group A. Although cardiac arrest time was longer in group C,postoperative CPK-MB was not significantly elevated, except in 4 patients. Postoperative data showed no significant differences between the two groups.
Conclusions: In our department, satisfactory clinical outcomes were obtained with combined operation AVR and CABG. Sufficient myocardial protection had an important effect on clinical outcomes.
書誌情報 弘前医学

巻 70, 号 2-4, p. 99-108, 発行日 2020-03-02
ISSN
収録物識別子タイプ ISSN
収録物識別子 0439-1721
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00211444
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
出版者
出版者 弘前大学大学院医学研究科
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