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The aortic valve alone group (group A) had 164 patients, with an average age of 71.6± 8.1 years. The combined operation group (group C) consisted of 54 patients, with an average age of 73.5±8.5 years. Aortic valve area and pressure gradient showed no significant differences between the two groups. In group C, an average of 2±0.8 vessels had CAD. Cold crystalloid cardioplegia according to left ventricular mass ± a terminal hot shot was used for all patients. Distal graft anastomosis was done after cardiac arrest and cardioplegia (1.5-fold normal) was injected additionally from the graft with severe proximal obstruction of the right coronary artery.\nResults: Group C included more patients with diabetes mellitus (DM, 43.4% vs. 26.8%) and low left ventricular ejection fraction( LVEF\u003c50%, 33.96% vs. 16.46%) than group A. On the other hand, the incidence of atrial fibrillation( AF, .77% vs. 13.41%) was significantly less in group C than in group A. Although cardiac arrest time was longer in group C,postoperative CPK-MB was not significantly elevated, except in 4 patients. Postoperative data showed no significant differences between the two groups.\nConclusions: In our department, satisfactory clinical outcomes were obtained with combined operation AVR and CABG. 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Outcome of concomitant surgical treatment in patients with coronary artery disease and severe aortic stenosis: A single-center study
http://hdl.handle.net/10129/00006959
http://hdl.handle.net/10129/00006959bf412b5f-3fdc-4f48-9b91-5697aafcfcf4
名前 / ファイル | ライセンス | アクション |
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Hirosaki Med J 70-2-4_99 (707.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-03-06 | |||||
タイトル | ||||||
タイトル | Outcome of concomitant surgical treatment in patients with coronary artery disease and severe aortic stenosis: A single-center study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | aortic stenosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | aortic valve replacement | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | coronary artery disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | coronary artery bypass grafting | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | combined operation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yu, Zaiqiang
× Yu, Zaiqiang× Daitoku, Kazuyuki× Yang, Wei× Kondo, Norihiro× Minakawa, Masahito× Fukuda, Ikuo |
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著者所属 | ||||||
Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Combined aortic valve replacement( AVR) and coronary artery bypass grafting(ABG)is mostly performed for patients with aortic stenosis( AS) and coronary artery disease( AD). Objectives: We aim to clarify that combined operation of AVR and CABG with adequate perioperative ardiac protection does not increase operative and postoperative risk. Methods: A total of 217 patients who underwent AVR for aortic stenosis alone or combined AVR and CABG from 1/2002 to 12/2015 were recruited. The aortic valve alone group (group A) had 164 patients, with an average age of 71.6± 8.1 years. The combined operation group (group C) consisted of 54 patients, with an average age of 73.5±8.5 years. Aortic valve area and pressure gradient showed no significant differences between the two groups. In group C, an average of 2±0.8 vessels had CAD. Cold crystalloid cardioplegia according to left ventricular mass ± a terminal hot shot was used for all patients. Distal graft anastomosis was done after cardiac arrest and cardioplegia (1.5-fold normal) was injected additionally from the graft with severe proximal obstruction of the right coronary artery. Results: Group C included more patients with diabetes mellitus (DM, 43.4% vs. 26.8%) and low left ventricular ejection fraction( LVEF<50%, 33.96% vs. 16.46%) than group A. On the other hand, the incidence of atrial fibrillation( AF, .77% vs. 13.41%) was significantly less in group C than in group A. Although cardiac arrest time was longer in group C,postoperative CPK-MB was not significantly elevated, except in 4 patients. Postoperative data showed no significant differences between the two groups. Conclusions: In our department, satisfactory clinical outcomes were obtained with combined operation AVR and CABG. Sufficient myocardial protection had an important effect on clinical outcomes. |
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書誌情報 |
弘前医学 巻 70, 号 2-4, p. 99-108, 発行日 2020-03-02 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科 |