WEKO3
アイテム
{"_buckets": {"deposit": "832179c3-96f3-4ab9-a5eb-54c7ea433be9"}, "_deposit": {"created_by": 3, "id": "3633", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "3633"}, "status": "published"}, "_oai": {"id": "oai:hirosaki.repo.nii.ac.jp:00003633", "sets": ["643"]}, "author_link": ["11463", "11094", "11870", "11872", "11866", "11842", "11868", "11874", "11869", "11512", "11875", "11863", "11458", "11506", "9403", "11871", "11876", "11865", "7528", "11862", "11459", "9404", "10562", "11867"], "item_3_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-11-29", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "Supplement", "bibliographicPageEnd": "S142", "bibliographicPageStart": "S137", "bibliographicVolumeNumber": "59", "bibliographic_titles": [{"bibliographic_title": "弘前医学"}]}]}, "item_3_description_17": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_3_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": " Retinoic acid-inducible gene-I (RIG-I) is a cytoplasmic protein regarded as putative RNA helicase.Immunohistochemical studies revealed high levels of RIG-I expression in epidermic cells in psoriasis, in macrophagesin atherosclerotic lesions and in glomeruli of lupus nephritis. RIG-I expression was also demonstrated in macrophagesand vascular endothelial cells in experimental animals with Listeria or Hanta virus infection. In vitro studies using cellcultures revealed the expression of RIG-I, in various cells including endothelial cells, macrophages and astroglial cells, inresponse to the stimulation with cytokines, lipopolysaccharide, double-stranded RNA, Listeria monocytogenes, etc. Thestudies employing the overexpression or RNA interference suggested that RIG-I is involved in the regulation of cytokineexpression including CXCL10/IP-10 and CCL5/RANTES. These results suggest that RIG-I constitutes a part of theintracellular pathway for the regulation of infl ammatory and immune responses.\n", "subitem_description_type": "Abstract"}]}, "item_3_description_7": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "弘前医学. 59(Suppl.), 2007, p.S137-S142", "subitem_description_type": "Other"}]}, "item_3_publisher_35": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "弘前大学大学院医学研究科・弘前医学会"}]}, "item_3_radio_42": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_radio_item": "Article"}]}, "item_3_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00211444", "subitem_source_identifier_type": "NCID"}]}, "item_3_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0439-1721", "subitem_source_identifier_type": "ISSN"}]}, "item_3_subject_19": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "491.8", "subitem_subject_scheme": "NDC"}]}, "item_3_subject_23": {"attribute_name": "NIIサブジェクト", "attribute_value_mlt": [{"subitem_subject": "基礎医学", "subitem_subject_scheme": "Other"}]}, "item_3_text_4": {"attribute_name": "著者所属", "attribute_value_mlt": [{"subitem_text_value": "Department of Vascular Biology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Molecular Pathology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Dermatology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Pediatrics, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Vascular Biology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Internal, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Dentistry and Oral, Surgery, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Vascular Biology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Dermatology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Dermatology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Pediatrics, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Internal, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Pediatrics, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Internal, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Dentistry and Oral, Surgery, Hirosaki University Graduate School of Medicine"}, {"subitem_text_value": "Department of Vascular Biology, Hirosaki University Graduate School of Medicine"}]}, "item_3_version_type_18": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Imaizumi, Tadaatsu"}], "nameIdentifiers": [{"nameIdentifier": "11458", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "318", "nameIdentifierScheme": "研究者総覧", "nameIdentifierURI": "http://hue2.jm.hirosaki-u.ac.jp/html/318_ja.html"}]}, {"creatorNames": [{"creatorName": "Mori, Fumiaki"}], "nameIdentifiers": [{"nameIdentifier": "9404", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yagihashi, Norito"}], "nameIdentifiers": [{"nameIdentifier": "11862", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kitamura, Hideo"}], "nameIdentifiers": [{"nameIdentifier": "11863", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sashinami, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "11506", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Koichi"}], "nameIdentifiers": [{"nameIdentifier": "11865", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamashita, Koji"}], "nameIdentifiers": [{"nameIdentifier": "11866", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Taima, Kageaki"}], "nameIdentifiers": [{"nameIdentifier": "11867", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "100000282", "nameIdentifierScheme": "研究者総覧", "nameIdentifierURI": "http://hue2.jm.hirosaki-u.ac.jp/html/100000282_ja.html"}]}, {"creatorNames": [{"creatorName": "Kubota, Kosei"}], "nameIdentifiers": [{"nameIdentifier": "11868", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "100000220", "nameIdentifierScheme": "研究者総覧", "nameIdentifierURI": "http://hue2.jm.hirosaki-u.ac.jp/html/100000220_ja.html"}]}, {"creatorNames": [{"creatorName": "Tanji, Kunikazu"}], "nameIdentifiers": [{"nameIdentifier": "11869", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "314", "nameIdentifierScheme": "研究者総覧", "nameIdentifierURI": "http://hue2.jm.hirosaki-u.ac.jp/html/314_ja.html"}]}, {"creatorNames": [{"creatorName": "Sakaki, Hirotaka"}], "nameIdentifiers": [{"nameIdentifier": "11870", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsumiya, Tomoh"}], "nameIdentifiers": [{"nameIdentifier": "11871", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "319", "nameIdentifierScheme": "研究者総覧", "nameIdentifierURI": "http://hue2.jm.hirosaki-u.ac.jp/html/319_ja.html"}]}, {"creatorNames": [{"creatorName": "Yoshida, Hidemi"}], "nameIdentifiers": [{"nameIdentifier": "11459", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mariya, Yasushi"}], "nameIdentifiers": [{"nameIdentifier": "10562", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakane, Hajime"}], "nameIdentifiers": [{"nameIdentifier": "11872", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "7528", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takanashi, Shingo"}], "nameIdentifiers": [{"nameIdentifier": "11874", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Wakabayashi, Koichi"}], "nameIdentifiers": [{"nameIdentifier": "9403", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yagihashi, Soroku"}], "nameIdentifiers": [{"nameIdentifier": "11842", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakane, Akio"}], "nameIdentifiers": [{"nameIdentifier": "11512", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ito, Etsuro"}], "nameIdentifiers": [{"nameIdentifier": "11094", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okumura, Ken"}], "nameIdentifiers": [{"nameIdentifier": "11875", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kimura, Hiroto"}], "nameIdentifiers": [{"nameIdentifier": "11876", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Satoh, Kei"}], "nameIdentifiers": [{"nameIdentifier": "11463", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-03-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "HirosakiMedJ_59_S137.pdf", "filesize": [{"value": "132.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 132100.0, "url": {"label": "HirosakiMedJ_59_S137.pdf", "url": "https://hirosaki.repo.nii.ac.jp/record/3633/files/HirosakiMedJ_59_S137.pdf"}, "version_id": "514b7f37-3e59-4cff-ac26-b7dcbbe2b858"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "RIG-I", "subitem_subject_scheme": "Other"}, {"subitem_subject": "infectious diseases", "subitem_subject_scheme": "Other"}, {"subitem_subject": "infl ammatory diseases", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Retinoic acid-inducible gene-I( RIG-I) and diseases", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Retinoic acid-inducible gene-I( RIG-I) and diseases"}]}, "item_type_id": "3", "owner": "3", "path": ["643"], "permalink_uri": "http://hdl.handle.net/10129/2227", "pubdate": {"attribute_name": "公開日", "attribute_value": "2009-09-18"}, "publish_date": "2009-09-18", "publish_status": "0", "recid": "3633", "relation": {}, "relation_version_is_last": true, "title": ["Retinoic acid-inducible gene-I( RIG-I) and diseases"], "weko_shared_id": 3}
Retinoic acid-inducible gene-I( RIG-I) and diseases
http://hdl.handle.net/10129/2227
http://hdl.handle.net/10129/222788677eb6-034f-4766-831c-919995968f95
名前 / ファイル | ライセンス | アクション |
---|---|---|
HirosakiMedJ_59_S137.pdf (132.1 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2009-09-18 | |||||
タイトル | ||||||
タイトル | Retinoic acid-inducible gene-I( RIG-I) and diseases | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | RIG-I | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | infectious diseases | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | infl ammatory diseases | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Imaizumi, Tadaatsu
× Imaizumi, Tadaatsu× Mori, Fumiaki× Yagihashi, Norito× Kitamura, Hideo× Sashinami, Hiroshi× Suzuki, Koichi× Yamashita, Koji× Taima, Kageaki× Kubota, Kosei× Tanji, Kunikazu× Sakaki, Hirotaka× Matsumiya, Tomoh× Yoshida, Hidemi× Mariya, Yasushi× Nakane, Hajime× Tanaka, Hiroshi× Takanashi, Shingo× Wakabayashi, Koichi× Yagihashi, Soroku× Nakane, Akio× Ito, Etsuro× Okumura, Ken× Kimura, Hiroto× Satoh, Kei |
|||||
著者所属 | ||||||
Department of Vascular Biology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Molecular Pathology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Dermatology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pediatrics, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Vascular Biology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Internal, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Dentistry and Oral, Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Vascular Biology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Dermatology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Dermatology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pediatrics, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Internal, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pediatrics, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Internal, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Dentistry and Oral, Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Vascular Biology, Hirosaki University Graduate School of Medicine | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Retinoic acid-inducible gene-I (RIG-I) is a cytoplasmic protein regarded as putative RNA helicase.Immunohistochemical studies revealed high levels of RIG-I expression in epidermic cells in psoriasis, in macrophagesin atherosclerotic lesions and in glomeruli of lupus nephritis. RIG-I expression was also demonstrated in macrophagesand vascular endothelial cells in experimental animals with Listeria or Hanta virus infection. In vitro studies using cellcultures revealed the expression of RIG-I, in various cells including endothelial cells, macrophages and astroglial cells, inresponse to the stimulation with cytokines, lipopolysaccharide, double-stranded RNA, Listeria monocytogenes, etc. Thestudies employing the overexpression or RNA interference suggested that RIG-I is involved in the regulation of cytokineexpression including CXCL10/IP-10 and CCL5/RANTES. These results suggest that RIG-I constitutes a part of theintracellular pathway for the regulation of infl ammatory and immune responses. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 弘前医学. 59(Suppl.), 2007, p.S137-S142 | |||||
書誌情報 |
弘前医学 巻 59, 号 Supplement, p. S137-S142, 発行日 2007-11-29 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
フォーマット | ||||||
内容記述タイプ | Other | |||||
内容記述 | application/pdf | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 491.8 | |||||
NIIサブジェクト | ||||||
主題Scheme | Other | |||||
主題 | 基礎医学 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||
資源タイプ | ||||||
値 | Article |