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"subitem_subject_scheme": "Other"}, {"subitem_subject": "内視鏡的切除術", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Histopathological Characteristics of Laterally Spreading Tumor(LST) Type Early Colorectal Cancer", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Histopathological Characteristics of Laterally Spreading Tumor(LST) Type Early Colorectal Cancer"}]}, "item_type_id": "3", "owner": "3", "path": ["653"], "permalink_uri": "http://hdl.handle.net/10129/5199", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-03-28"}, "publish_date": "2014-03-28", "publish_status": "0", "recid": "3766", "relation": {}, "relation_version_is_last": true, "title": ["Histopathological 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Histopathological Characteristics of Laterally Spreading Tumor(LST) Type Early Colorectal Cancer
http://hdl.handle.net/10129/5199
http://hdl.handle.net/10129/519917b94087-f4c4-4a12-b272-2ac1c6082341
名前 / ファイル | ライセンス | アクション |
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HirosakiMedJ_64(2-4)_158.pdf (2.3 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-03-28 | |||||
タイトル | ||||||
タイトル | Histopathological Characteristics of Laterally Spreading Tumor(LST) Type Early Colorectal Cancer | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Colorectal cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | early cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | laterally spreading tumor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | endoscopic resection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 大腸・直腸癌 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 早期癌 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 側方伸展型腫瘍 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 内視鏡的切除術 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takasugi, Kaori
× Takasugi, Kaori× Morohashi, Satoko× Haga, Toshihiro× Toba, Takahito× Seino, Hiroko× Wu, Yunyan× Suzuki, Takahiro× Hanabata, Norihiro× Sasaki, Yoshihiro× Fukuda, Shinsaku× Kijima, Hiroshi |
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著者(ヨミ) | ||||||
姓名 | タカスギ, カオリ | |||||
著者(ヨミ) | ||||||
姓名 | モロハシ, サトコ | |||||
著者(ヨミ) | ||||||
姓名 | ハガ, トシヒロ | |||||
著者(ヨミ) | ||||||
姓名 | トバ, タカヒト | |||||
著者(ヨミ) | ||||||
姓名 | セイノ, ヒロコ | |||||
著者(ヨミ) | ||||||
姓名 | ゴ, ウンエン | |||||
著者(ヨミ) | ||||||
姓名 | スズキ, タカヒロ | |||||
著者(ヨミ) | ||||||
姓名 | ハナバタ, ノリヒロ | |||||
著者(ヨミ) | ||||||
姓名 | ササキ, ヨシヒロ | |||||
著者(ヨミ) | ||||||
姓名 | フクダ, シンサク | |||||
著者(ヨミ) | ||||||
姓名 | キジマ, ヒロシ | |||||
著者別名 | ||||||
姓名 | 高杉, かおり | |||||
著者別名 | ||||||
姓名 | 諸橋, 聡子 | |||||
著者別名 | ||||||
姓名 | 羽賀, 敏博 | |||||
著者別名 | ||||||
姓名 | 鳥羽, 崇仁 | |||||
著者別名 | ||||||
姓名 | 清野, 浩子 | |||||
著者別名 | ||||||
姓名 | 呉, 雲燕 | |||||
著者別名 | ||||||
姓名 | 鈴木, 貴弘 | |||||
著者別名 | ||||||
姓名 | 花畑, 憲洋 | |||||
著者別名 | ||||||
姓名 | 佐々木, 賀広 | |||||
著者別名 | ||||||
姓名 | 福田, 眞作 | |||||
著者別名 | ||||||
姓名 | 鬼島, 宏 | |||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine / Department of Gastroenterology and Hematology, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine / Department of Gastroenterology and Hematology, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterology and Hematology, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Department of Medical Informatics, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterology and Hematology, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
Departments of Pathology and Bioscience, Hirosaki University Graduates School of Medicine | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 / 弘前大学大学院医学研究科消化器血液内科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 / 弘前大学大学院医学研究科消化器血液内科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科消化器血液内科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科医学医療情報学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科消化器血液内科学講座 | ||||||
著者所属 | ||||||
弘前大学大学院医学研究科病理生命科学講座 | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Recently, laterally spreading tumor (LST) of early colorectal carcinoma has been treated by endoscopic submucosal dissection (ESD) more frequently. Many cases of early colorectal carcinomas are diagnosed as well differentiated adenocarcinomas, but histological and/or immunohistorogical heterogeneity is often seen in LSTs. In this study, we analyzed morphological characteristics of 61 lesions of LST-type early colorectal carcinoma by using histolosical and immunohistochemical procedures. Presence of high grade atypia components was significantly correlated with depth of submucosal invasion (P=0.0102), and these were predominantly located to the invasive front(deep part) of the submucosal carcinoma. Allred scores of p53 and Ki-67 labeling indices were increased in the component of high grade atypia regardless of depth of invasion. Expressions of CDX2 and CD10 were significantly upregulated in a depth-of-invasion dependent manner, and these tended to be highly expressed in the high grade atypias. In onclusion, the present study indicates that the majority of LST is histologically heterogeneic. The component of high grade atypia of LST upregulates cell proliferation, which may leed to increase the malignant potential of LST for invading the submucosa. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 弘前医学. 64(2-4), 2014, p.158-169 | |||||
書誌情報 |
弘前医学 巻 64, 号 2-4, p. 158-169, 発行日 2014-02-28 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 494.5 | |||||
その他のタイトル | ||||||
その他のタイトル | 側方伸展型発育を示す早期大腸癌の組織学的特徴 | |||||
タイトル(ヨミ) | ||||||
その他のタイトル | ソクホウ シンテンガタ ハツイク オ シメス ソウキ ダイチョウガン ノ ソシキガクテキ トクチョウ | |||||
NIIサブジェクト | ||||||
主題Scheme | Other | |||||
主題 | 医学 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||
資源タイプ | ||||||
値 | Article |