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Custom Synthesis of Hyaluronan/Chondroitin Sulfate Hybrid Oligosaccharides : For Future Medical Applications
http://hdl.handle.net/10129/4866
http://hdl.handle.net/10129/4866ba673039-e947-4d0d-bda2-05b8d73e14db
名前 / ファイル | ライセンス | アクション |
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HirosakiMedJ_64_S53.pdf (214.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-04-30 | |||||
タイトル | ||||||
タイトル | Custom Synthesis of Hyaluronan/Chondroitin Sulfate Hybrid Oligosaccharides : For Future Medical Applications | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hyaluronan | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | chondroitin sulfate | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hyaluronidase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | transglycosylation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | oligosaccharide | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kakizaki, Ikuko
× Kakizaki, Ikuko× Suto, Shinichiro× Tatara, Yota× Endo, Masahiko |
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著者(ヨミ) | ||||||
姓名 | カキザキ, イクコ | |||||
著者(ヨミ) | ||||||
姓名 | ストウ, シンイチロウ | |||||
著者(ヨミ) | ||||||
姓名 | タタラ, ヨウタ | |||||
著者(ヨミ) | ||||||
姓名 | エンドウ, マサヒコ | |||||
著者別名 | ||||||
姓名 | 柿崎, 育子 | |||||
著者別名 | ||||||
姓名 | 須藤, 晋一郎 | |||||
著者別名 | ||||||
姓名 | 多田羅, 洋太 | |||||
著者別名 | ||||||
姓名 | 遠藤, 正彦 | |||||
著者所属 | ||||||
Department of Glycotechnology, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Glycomedicine, Hirosaki University Graduate School of Medicine | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Hyaluronan and chondroitin sulfate sugar chains play important roles as major components of extracellular matrix. They are attractive molecules for biochemical research and are also used in pharmaceutical agents. However, details of the relationships between their oligosaccharide structures and functions are not known because of a lack of availability of model oligosaccharides with known structures. In order to, in the future, investigate their functions based on structure, we synthesized hybrid oligosaccharides by the in vitro transglycosylation reaction of hyaluronidase using various combinations of acceptors and donors. A total of 18 kinds of pyridylaminated hyaluronan/chondroitin sulfate hybrid oligosaccharides (from octasaccahride to dodecasaccharide), which have not been found in nature, were synthesized. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 弘前医学. 64(Suppl.), 2013, p.S53-S57 | |||||
書誌情報 |
弘前医学 巻 64, 号 Supplement, p. S53-S57, 発行日 2013-04-02 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 490 | |||||
NIIサブジェクト | ||||||
主題Scheme | Other | |||||
主題 | 医学 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||
資源タイプ | ||||||
値 | Article |