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MUC5AC-Negative Phenotype is Correlated with Poor Patient Prognosis of Pancreas Head Ductal Carcinoma.
http://hdl.handle.net/10129/5563
http://hdl.handle.net/10129/55639f45fe2a-61e0-4156-b0da-74b1bce20978
名前 / ファイル | ライセンス | アクション |
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HirosakiMedJ_66(1)_28.pdf (1.3 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-05-25 | |||||
タイトル | ||||||
タイトル | MUC5AC-Negative Phenotype is Correlated with Poor Patient Prognosis of Pancreas Head Ductal Carcinoma. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mucin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | MUC5AC | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pancreas cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | bile duct cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | patient prognosis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Sakuraba, Shingo
× Sakuraba, Shingo× Morohashi, Satoko× Yoshizawa, Tadashi× Tsutsumi, shinji× Kimura, Norihisa× Kudo, Daisuke× Ishido, Keinosuke× Toyoki, Yoshikazu× Hakamada, Kenichi× Kijima, Hiroshi |
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著者所属 | ||||||
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Both pancreas head ductal carcinoma( PHDC) and distal bile duct carcinoma( DBDC) are located within the pancreas head/intra-pancreatic bile duct region, and are the most aggressive malignancies with poor patient prognosis. In the present study, we demonstrated clinicopathological features and patients prognosis of PHDC/DBDC. We examined total 87 surgically resected cases of PHDC (40 cases) and DBDC (47 cases). PHDC showed frequent neural invasion (85.0%) and lymph node metastasis (77.5%), compared with DBDC (57.4% and 40.4% respectively), resulting in the poorer prognosis( P=0.0219) than DBDC. In addition, PHDC expressed MUC2( 10.0%)and MUC6 (25.0%) less frequently, compared with DBDC (36.2% and 55.3%, respectively). MUC5AC-negative PHDC exhibited significantly poorer patient’s prognosis, compared with MUC5AC-positive PHDC (P=0.0111), MUC5ACpositive DBDC (P=0.000162), and MUC5AC-negative DBDC (P=0.00416). In conclusion, MUC5AC-negative PHDC showed significantly poor patient’s prognosis. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 弘前医学. 66, 2015, p.28-37 | |||||
書誌情報 |
弘前医学 巻 66, 号 1, p. 28-37, 発行日 2015-04-06 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 490 | |||||
NIIサブジェクト | ||||||
主題Scheme | Other | |||||
主題 | 医学 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||
資源タイプ | ||||||
値 | Article |