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Molecular cloning of medaka orexin and orexin receptor and decreased spontaneous movement in response to an orexin inhibitor
http://hdl.handle.net/10129/00007199
http://hdl.handle.net/10129/00007199f54f5db3-8fd4-4692-b6ca-35ab2f79b596
名前 / ファイル | ライセンス | アクション |
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HirosakiMedJ_71(1)_55 (387.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-11-13 | |||||
タイトル | ||||||
タイトル | Molecular cloning of medaka orexin and orexin receptor and decreased spontaneous movement in response to an orexin inhibitor | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | medaka | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | orexin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cDNA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | neuropeptide | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fish | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Niisawa, Tomoyuki
× Niisawa, Tomoyuki× Naruta, Naoki× Murakami, Agnieszka M× Yonekura, Manabu× Hirota, Kazuyoshi× Itagaki, Shirou× Murakami, Manabu |
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著者所属 | ||||||
Department of Pharmacology, Hirosaki University | ||||||
著者所属 | ||||||
Department of Pharmacology, Hirosaki University | ||||||
著者所属 | ||||||
Department of Pharmacology, Hirosaki University | ||||||
著者所属 | ||||||
Department of Cardiology and Nephrology, Hirosaki University | ||||||
著者所属 | ||||||
Department of Anesthesiology, Hirosaki University, Graduate School of Medicine | ||||||
著者所属 | ||||||
Collaboration Center for Community and Industry, Sapporo Medical University | ||||||
著者所属 | ||||||
Department of Pharmacology, Hirosaki University | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Orexin (hypocretin) is a neuropeptide secreted by hypothalamic neurons that is activated duringmotivating behaviors and active waking. Our knowledge of orexin is mainly limited to mammalian species, such ashumans, mice, and rats. In the present study, we cloned orexin and its receptor from the medaka brain. Additionally,we analyzed the effect of an orexin inhibitor (SB-649868) on spontaneous behavior. The orexin inhibitor decreasedresults indicate that medaka might be a suitable animal model for neurological behavioral studies. | |||||
書誌情報 |
弘前医学 巻 71, 号 1, p. 55-64, 発行日 2020-10-30 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科 | |||||
資源タイプ | ||||||
値 | Article |