{"created":"2025-01-07T04:28:53.905605+00:00","id":2000722,"links":{},"metadata":{"_buckets":{"deposit":"08222f41-c29c-4a86-a641-a63ec631e70e"},"_deposit":{"created_by":11,"id":"2000722","owner":"11","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"2000722"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:02000722","sets":["557:666:1733727873643"]},"author_link":[],"control_number":"2000722","item_1735019115310":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Persistent idiopathic dentoalveolar pain (PDAP), previously referred to as atypical odontalgia, is a chronic dental pain that occurs  without signs of pathology. PDAP is considered a diagnosis of exclusion, and its definition is currently under refinement and remains ambiguous. The metabolite known as 3-hydroxybutyrate (3HB) has garnered significant interest as a potential indicator for both depression and chronic psychogenic pain. We investigated the characteristics of patients with PDAP and hypothesized that serum 3HB could support the diagnosis of PDAP.\nSubjects and Methods: Forty-one patients with PDAP and 167 patients with odontogenic toothache were investigated regarding depression and anxiety scales in addition to the general dental evaluation. Blood tests including high-sensitivity CRP, HbA1c, and 3HB were performed for all patients. Associations between PDAP and patients’ varying characteristics were investigated using hierarchical multivariate logistic regression analyses.\nResults: There were more females, current smokers, patients with orofacial pain (such as temporomandibular joint pain, glossalgia, and headache), and people with elevated 3HB levels among patients with PDAP than among control participants. Multivariate logistic regression analyses predicting patients with PDAP identified the female sex (odds ratio [OR]: 4.16), current smoking (OR: 14.9), glossalgia (OR: 19.8) a high CES-D score (≥16) (OR: 5.98), and elevated serum 3HB (≥80 μmol/L) (OR: 18.4) factors significantly associated with PDAP.\nConclusion: Our results demonstrated that serum 3HB levels could be elevated in patients with PDAP compared to other types of odontogenic pain, although 3HB was not specific to PDAP. Based on our findings, five factors - female sex, current smoking, depressive tendencies, chronic orofacial pains, and high serum 3HB levels - could be useful for diagnosing PDAP.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_1735020952570":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.2147/JPR.S436034","subitem_relation_type_select":"DOI"}}]},"item_30001_access_rights4":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_30001_bibliographic_information17":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-11-22","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4013","bibliographicPageStart":"4005","bibliographicVolumeNumber":"16","bibliographic_titles":[{"bibliographic_title":"Journal of Pain Research","bibliographic_titleLang":"en"}]}]},"item_30001_creator2":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"玉木, 克弥","creatorNameLang":"ja"}]}]},"item_30001_date_granted20":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2024-09-30"}]},"item_30001_degree_grantor21":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"弘前大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"11101","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_30001_degree_name19":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_30001_description8":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Author: Katsuya Tamaki, Norihiro Saito, Hirofumi Tomita","subitem_description_language":"en","subitem_description_type":"Other"},{"subitem_description":"Citation: Journal of Pain Research :16:4005-4013, 2023 Nov 22","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_30001_dissertation_number18":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第2297号"}]},"item_30001_file22":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-01-07"}],"filename":"tdm_2297_tamaki.pdf","filesize":[{"value":"306 KB"}],"format":"application/pdf","licensetype":"license_3","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://hirosaki.repo.nii.ac.jp/record/2000722/files/tdm_2297_tamaki.pdf"},"version_id":"3da4c1b3-cbe1-4907-8e53-339c6d9f2d33"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-01-07"}],"filename":"tdm_2297_tamaki_a1.pdf","filesize":[{"value":"188 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"内容要旨","objectType":"abstract","url":"https://hirosaki.repo.nii.ac.jp/record/2000722/files/tdm_2297_tamaki_a1.pdf"},"version_id":"8787fc8f-f85c-4504-8ca4-5058d625eb2e"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-01-07"}],"filename":"tdm_2297_tamaki_a2.pdf","filesize":[{"value":"198 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"審査要旨","objectType":"abstract","url":"https://hirosaki.repo.nii.ac.jp/record/2000722/files/tdm_2297_tamaki_a2.pdf"},"version_id":"2f6ec1f0-43be-4d68-84b5-b0cf7239c89f"}]},"item_30001_language10":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_30001_publisher9":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Dovepress","subitem_publisher_language":"en"}]},"item_30001_resource_type11":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_30001_rights5":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"© 2023 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.","subitem_rights_language":"en"}]},"item_30001_source_identifier16":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1178-7090","subitem_source_identifier_type":"EISSN"}]},"item_30001_subject7":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"persistent idiopathic dentoalveolar pain","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"atypical odontalgia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"3-hydroxybutyrate","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"temporomandibular disorder","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"orofacial pain","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_30001_title0":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Serum 3-Hydroxybutyrate is Expected to Serve as One of the Supportive Diagnostic Markers of Persistent Idiopathic Dentoalveolar Pain (PDAP)","subitem_title_language":"en"}]},"item_30001_version_type12":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_title":"Serum 3-Hydroxybutyrate is Expected to Serve as One of the Supportive Diagnostic Markers of Persistent Idiopathic Dentoalveolar Pain (PDAP)","item_type_id":"40034","owner":"11","path":["1733727873643"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2025-01-07"},"publish_date":"2025-01-07","publish_status":"0","recid":"2000722","relation_version_is_last":true,"title":["Serum 3-Hydroxybutyrate is Expected to Serve as One of the Supportive Diagnostic Markers of Persistent Idiopathic Dentoalveolar Pain (PDAP)"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2025-01-28T05:07:54.339915+00:00"}