{"created":"2025-06-19T00:41:29.252183+00:00","id":2000941,"links":{},"metadata":{"_buckets":{"deposit":"18b4a5d0-b9bf-4488-8cb3-6536ed53f00b"},"_deposit":{"created_by":11,"id":"2000941","owner":"11","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"2000941"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:02000941","sets":["557:1754614239215:666:1747629202301"]},"author_link":[],"control_number":"2000941","item_1735019115310":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Ultraviolet-C (UV-C) at a wavelength of 254 nm is used for disinfection but cannot be used in dwelling space because it is harmful to the human body, while 222-nm Far UV-C shows germicidal effect and poses little hazardous effect to human. Formation of cyclobutane pyrimidine dimers (CPD) of DNA is a main mechanism of UV-C germicidal effect. CPD formed by irradiation with 254-nm UV-C is repaired and bacterial proliferation is recovered by photoreactivation. In this study, we investigated photoreactivation of Staphylococcus aureus irradiated with 222-nm Far UV-C. The proliferative effect of 222-nm Far UV-C irradiated S. aureus by photoreactivation was inferior to that of irradiated with 254-nm UV-C. The 254-nm UV-C wavelength and 222- nm Far UV-C induced CPD in S. aureus cells, and the same level of CPD was repaired in cells irradiated with either UV-C after photoreactivation. It has been reported that UV-C induces generation of reactive oxygen species (ROS) in bacteria, and that ROS oxidize and inactivate a variety of biomolecules in bacteria. The present study showed that more ROS-producing S. aureus were observed after irradiation with 222-nm Far UV-C compared with 254-nm UV-C. These results indicate that ROS may be involved in lower recovery of 222-nm Far UV-C irradiated S. aureus by photoreactivation.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_1735020952570":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/php.14065","subitem_relation_type_select":"DOI"}}]},"item_1756857892097":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_30001_access_rights4":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_30001_creator2":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"福士, 理沙子","creatorNameLang":"ja"}]}]},"item_30001_date_granted20":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2025-03-24"}]},"item_30001_degree_grantor21":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"弘前大学"}]}]},"item_30001_degree_name19":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_30001_dissertation_number18":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第2324号"}]},"item_30001_file22":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-06-18"}],"filename":"tdm_2324_fukushi.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://hirosaki.repo.nii.ac.jp/record/2000941/files/tdm_2324_fukushi.pdf"},"version_id":"588be6fc-4065-43e6-ae12-3c9cc962e9cd"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-06-18"}],"filename":"tdm_2324_fukushi_a1.pdf","filesize":[{"value":"226 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"内容要旨","objectType":"abstract","url":"https://hirosaki.repo.nii.ac.jp/record/2000941/files/tdm_2324_fukushi_a1.pdf"},"version_id":"4e46a64b-8bb4-47bc-b2b4-2f7d0c39605c"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-06-18"}],"filename":"tdm_2324_fukushi_a2.pdf","filesize":[{"value":"119 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"審査要旨","objectType":"abstract","url":"https://hirosaki.repo.nii.ac.jp/record/2000941/files/tdm_2324_fukushi_a2.pdf"},"version_id":"fddb4423-4949-494f-a32c-52c0e93c3015"}]},"item_30001_language10":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_30001_publisher9":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley","subitem_publisher_language":"en"}]},"item_30001_rights5":{"attribute_name":"権利情報","attribute_value_mlt":[{"subitem_rights":"This is the peer reviewed version of the following article: Reactive oxygen species are involved in inhibition of photoreactivation of Staphylococcus aureus irradiated with 222-nm Far ultraviolet C, which has been published in final form at https://doi.org/10.1111/php.14065. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wileyʼs version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.","subitem_rights_language":"en"}]},"item_30001_title0":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Reactive oxygen species are involved in inhibition of photoreactivation of Staphylococcus aureus irradiated with 222-nm Far ultraviolet C","subitem_title_language":"en"}]},"item_30001_version_type12":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_title":"Reactive oxygen species are involved in inhibition of photoreactivation of Staphylococcus aureus irradiated with 222-nm Far ultraviolet C","item_type_id":"40034","owner":"11","path":["1747629202301"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2025-06-18"},"publish_date":"2025-06-18","publish_status":"0","recid":"2000941","relation_version_is_last":true,"title":["Reactive oxygen species are involved in inhibition of photoreactivation of Staphylococcus aureus irradiated with 222-nm Far ultraviolet C"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2025-09-19T02:29:06.684956+00:00"}