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Effect of Superior Vena Cava Isolation Added to Pulmonary Vein Isolation on the Postprocedural Heart Rates of Patients With Paroxysmal Atrial Fibrillation
http://hdl.handle.net/10129/0002001851
http://hdl.handle.net/10129/0002001851fb08067f-8827-4714-93a0-513743d519d1
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本文 (730 KB)
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内容要旨 (173 KB)
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審査要旨 (281 KB)
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| アイテムタイプ | リポジトリ登録用アイテムタイプ（シンプル）(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2025-11-18 | |||||||||
| タイトル | ||||||||||
| タイトル | Effect of Superior Vena Cava Isolation Added to Pulmonary Vein Isolation on the Postprocedural Heart Rates of Patients With Paroxysmal Atrial Fibrillation | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| その他のタイトル | ||||||||||
| その他のタイトル | 発作性心房細動患者における肺静脈隔離に上大静脈隔離を追加した際の術後心拍数への影響 | |||||||||
| 言語 | ja | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | atrial fibrillation | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | catheter ablation | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | superior vena cava | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | heart rate | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | beta-blocker | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | embargoed access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_f1cf | |||||||||
| 著者 |
根岸, 耕大
× 根岸, 耕大
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Background: Pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (AF) is often associated with an increased resting heart rate (rHR) due to neuromodulation of the cardiac autonomic plexus. Changes in the rHR by adding superior vena cava (SVC) isolation (SVCI) to PVI have not been fully elucidated. Methods: We retrospectively analyzed 257 consecutive patients with paroxysmal AF undergoing ablation index-guided AF ablation from January 2021 to June 2022. In patients with SVC myocardial sleeve ≥20 mm above the sinus node, circumferential SVCI was added. Consequently, PVI only was done in 110 patients and PVI plus SVCI was in 147 patients. We analyzed rHRs obtained at baseline and 1, 3, 6, and 12 months after the ablation procedure using a linear mixed-effects model. Predictors of increases in rHRs >20% from baseline values were also examined. Results: The characteristics of the patients with PVI only versus PVI+SVCI were as follows: mean age, 70.2±10.6 versus 65.3±10.3 years, respectively (p<0.001); percentage of females, 44.5% versus 28.6%, respectively (p=0.009); and baseline rHR, 62.5±11.4 versus 61.0±9.2 beats/minute, respectively (p=0.239). At one month after the procedure, PVI+SVCI patients had a significantly higher rHR by 9.04 beats/minute (95% confidence interval [CI, 6.57–11.51], p < 0.01) compared to PVI-only and maintained significantly increased rHRs throughout the 12-month period. Multivariate logistic regression analysis revealed that SVCI added to PVI had a positive impact on rHRs increase >20% (odds ratio [OR], 3.59 [95% CI 2.09-6.18], p<0.001), while beta- blockers showed a negative impact (OR, 0.51 [95% CI 0.30-0.87], p=0.01). Conclusion: The addition of SVCI to PVI led to increases in rHRs, presumably because of additional modulation of the cardiac autonomic plexus. |
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| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Author(s): Negishi, Kodai ; Okumura, Ken ; Okamatsu, Hideharu ; Tsurugi, Takuo ; Tanaka, Yasuaki ; Nakao, Koichi ; Sakamoto, Tomohiro ; Koyama, Junjiro ; Tomita, Hirofumi | |||||||||
| 言語 | en | |||||||||
| 書誌情報 |
en : Journal of Cardiovascular Electrophysiology 巻 36, 号 7, p. 1504-1511, 発行日 2025-04-28 |
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| 関連情報 | ||||||||||
| 言語 | en | |||||||||
| 関連名称 | This is the peer reviewed version of the following article: Effect of Superior Vena Cava Isolation Added to Pulmonary Vein Isolation on the Postprocedural Heart Rates of Patients With Paroxysmal Atrial Fibrillation, which has been published in final form at https://doi.org/10.1111/jce.16699. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. | |||||||||
| 関連情報 | ||||||||||
| 言語 | en | |||||||||
| 関連名称 | © 2025 Wiley Periodicals LLC. | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | EISSN | |||||||||
| 収録物識別子 | 1540-8167 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isVersionOf | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1111/jce.16699 | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | NA | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_be7fb7dd8ff6fe43 | |||||||||
| 出版者 | ||||||||||
| 出版者 | Wiley | |||||||||
| 言語 | en | |||||||||
| 学位名 | ||||||||||
| 学位名 | 博士（医学） | |||||||||
| 言語 | ja | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関名 | 弘前大学 | |||||||||
| 言語 | ja | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2025-09-30 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第2337号 | |||||||||
