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Effect of visceral fat on onset of metabolic syndrome
http://hdl.handle.net/10129/0002001853
http://hdl.handle.net/10129/00020018535cdfe8f8-bd39-4f7c-8a6b-027fe3f11b67
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本文 (1.4 MB)
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内容要旨 (175 KB)
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審査要旨 (142 KB)
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| アイテムタイプ | リポジトリ登録用アイテムタイプ（シンプル）(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2025-11-18 | |||||||||
| タイトル | ||||||||||
| タイトル | Effect of visceral fat on onset of metabolic syndrome | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Metabolic syndrome (MetS) | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Visceral fat | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Onset prediction models | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | SHapley additive exPlanations (SHAP) | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Machine learning | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Early detection | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 著者 |
武士田, 寛人
× 武士田, 寛人
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | This study analysed the effects of visceral fat on metabolic syndrome (MetS) and developed an algorithm to predict its onset using health examination data from the Iwaki Health Promotion Project in Japan. The dataset included 213 cases of MetS onset within three years and 1320 non-onset cases. The data was split into training and test sets with an 8:2 ratio. In the training set, the MetS onset group had significantly higher visceral fat area than the non-onset group (p < 0.00001). A cut-off value of 82 cm2 for the visceral fat area was determined, with an AUC of 0.86. Additionally, a machine learning algorithm utilizing seven non-invasive factors, including visceral fat, achieved high accuracy with a five-fold cross-validation AUC of 0.90 in the training set and 0.88 in the test set. Visceral fat was identified as the main factor, as supported by the SHAP value. In conclusion, this study found visceral fat to be crucial in predicting the onset of MetS, and a high-accuracy onset prediction algorithm based on non-invasive parameters, including visceral fat, was developed. |
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| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Author(s): Bushita, Hiroto ; Ozato, Naoki ; Mori, Kenta ; Kawada, Hiromitsu ; Katsuragi, Yoshihisa ; Osaki, Noriko ; Mikami, Tatsuya ; Itoh, Ken ; Murashita, Koichi ; Nakaji, Shigeyuki ; Tamada, Yoshinori | |||||||||
| 言語 | en | |||||||||
| 書誌情報 |
en : Scientific Reports 巻 15, p. 19012, 発行日 2025-05-30 |
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| 関連情報 | ||||||||||
| 関連タイプ | isSupplementedBy | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1038/s41598-025-20722-2 | |||||||||
| 言語 | en | |||||||||
| 関連名称 | 06 October 2025A Correction to this paper has been published. | |||||||||
| 関連情報 | ||||||||||
| 言語 | en | |||||||||
| 関連名称 | The original online version of this Article was revised: The original version of this Article contained errors. Modifications have been made to the Figures, the Methods section and the Supplementary Information. Full information regarding the corrections made can be found in the correction for this Article. | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | EISSN | |||||||||
| 収録物識別子 | 2045-2322 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1038/s41598-025-01389-1 | |||||||||
| 権利情報 | ||||||||||
| 権利情報 | Effect of visceral fat on onset of metabolic syndrome Author: Hiroto Bushita et al Publication: Scientific Reports Publisher: Springer Nature Date: May 30, 2025 Copyright © 2025, The Author(s) | |||||||||
| 言語 | en | |||||||||
| 権利情報 | ||||||||||
| 権利情報 | Creative Commons This is an open access article distributed under the terms of the Creative Commons CC BY license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You are not required to obtain permission to reuse this article. To request permission for a type of use not listed, please contact Springer Nature | |||||||||
| 言語 | en | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 出版者 | ||||||||||
| 言語 | en | |||||||||
| 学位名 | ||||||||||
| 学位名 | 博士（医学） | |||||||||
| 言語 | ja | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関名 | 弘前大学 | |||||||||
| 言語 | ja | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2025-09-30 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第2339号 | |||||||||
