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  1. 30 医学部・医学研究科・附属病院
  2. 30d 学術雑誌論文
  3. 30d-01 学術雑誌論文(医学研究科)

Incidence and Predictors of Appropriate Implantable Cardioverter Defibrillator Therapy in Japanese Ischemic Heart Disease Patients

http://hdl.handle.net/10129/0002001980
http://hdl.handle.net/10129/0002001980
d6304040-07a4-4835-9029-ec4bedce5a43
名前 / ファイル ライセンス アクション
89_CJ-24-0436.pdf 89_CJ-24-0436.pdf (1.6 MB)
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アイテムタイプ リポジトリ登録用アイテムタイプ(シンプル)(1)
公開日 2026-03-23
タイトル
タイトル Incidence and Predictors of Appropriate Implantable Cardioverter Defibrillator Therapy in Japanese Ischemic Heart Disease Patients
言語 en
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 Hanada, Kenji

× Hanada, Kenji

en Hanada, Kenji

ja 弘前大学大学院医学研究科

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Sasaki, Shingo

× Sasaki, Shingo

en Sasaki, Shingo

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Kinjo, Takahiko

× Kinjo, Takahiko

en Kinjo, Takahiko

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著者所属
言語 en
値 Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine
抄録
内容記述タイプ Abstract
内容記述 Background: Although the efficacy of an implantable cardioverter defibrillator (ICD) in preventing sudden cardiac death is well established, the incidence and predictors of appropriate ICD therapy in Japanese ischemic heart disease (IHD) patients remain unclear.

Methods and Results: We retrospectively studied Japanese 141 IHD patients undergoing transvenous ICD or cardiac resynchronization therapy with a defibrillator (CRT-D) implantation for primary or secondary prevention at Hirosaki University Hospital. Over a mean (±SD) follow-up period of 5.5±2.8 years, the incidence of appropriate ICD therapy was similar in the primary and secondary prevention groups, although it was relatively more frequent in the first 2 years in the secondary prevention group. Four patients died due to sustained ventricular tachycardia (VT) or ventricular fibrillation (VF), mainly due to post-shock pulseless electrical activity. Once patients had received their first appropriate ICD therapy, 49.2% received second appropriate ICD therapy within 6 months. Cox proportional hazard analysis revealed that sustained VT as an index life-threatening ventricular tachyarrhythmia before ICD/CRT-D implantation was an independent predictor of appropriate ICD therapy, but VF was not.

Conclusions: The incidence of appropriate ICD therapy was comparable in primary and secondary prevention among Japanese IHD patients. We need to recognize the high-risk period for second appropriate ICD therapy after the first therapy and sustained VT as index life-threatening ventricular tachyarrhythmia as a risk factor for appropriate ICD therapy.
言語 en
内容記述
内容記述タイプ Other
内容記述 Author(s):Hanada, Kenji ; Sasaki, Shingo ; Kinjo, Takahiko ; Shikanai, Shun ; Yamazaki, Ken ; Kato, Tomo ; Tsushima, Michiko ; Senoo, Maiko; Narita, Noritomo ; Ichikawa, Hiroaki ; Shibutani, Shuji ; Yokoyama, Hiroaki ; Yokota, Takashi ; Okumura, Ken ; Tomita, Hirofumi
言語 en
書誌情報 en : CIRCULATION JOURNAL

巻 89, 号 3, p. 354-363
ISSN
収録物識別子タイプ PISSN
収録物識別子 1346-9843
ISSN
収録物識別子タイプ EISSN
収録物識別子 1347-4820
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 https://doi.org/10.1253/circj.CJ-24-0436
権利情報
権利情報 © 2025, THE JAPANESE CIRCULATION SOCIETY
言語 en
権利情報
権利情報 This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license. https://creativecommons.org/licenses/by-nc-nd/4.0/
言語 en
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
出版者
出版者 The Japanese Circulation Society
言語 en
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