| アイテムタイプ |
リポジトリ登録用アイテムタイプ（フル）(1) |
| 公開日 |
2026-03-25 |
| タイトル |
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|
タイトル |
Psoas muscle index as an independent prognostic factor in patients with unresectable pancreatic cancer: A retrospective analysis |
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言語 |
en |
| 作成者 |
Chen, Yu
| en |
Chen, Yu
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Department of Medical Oncology, Hirosaki University Graduate School of Medicine
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Search repository
Tatsuo, Soichiro
| en |
Tatsuo, Soichiro
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Department of Radiology, Hirosaki University Graduate School of Medicine
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Search repository
Shintaku, Tomohiro
| en |
Shintaku, Tomohiro
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Department of Radiology, Hirosaki University Graduate School of Medicine
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Search repository
Saito, Kensuke
| en |
Saito, Kensuke
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Department of Medical Oncology, Hirosaki University Graduate School of Medicine
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Search repository
Kakeda, Shingo
| en |
Kakeda, Shingo
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Department of Radiology, Hirosaki University Graduate School of Medicine
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Search repository
Sato, Atsushi
| en |
Sato, Atsushi
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Department of Medical Oncology, Hirosaki University Graduate School of Medicine
|
Search repository
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| アクセス権 |
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|
アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: Chemotherapy remains the standard treatment for unresectable pancreatic cancer （UPC）, which carries poor prognosis. Although skeletal muscle loss and poor muscle quality have been recognized as prognostic factors in patients with resectable pancreatic cancer, their significance in UPC remains unclear. Methods: We retrospectively analyzed 120 UPC patients who received first-line chemotherapy between 2013 and 2021. The psoas muscle index （PMI） and intramuscular adipose tissue content （IMAC） were measured via computed tomography （CT） before treatment and at the first post-treatment evaluation. Associations between baseline values and early changes and survival outcomes were then evaluated. Results: Low PMI at baseline and first post-treatment CT, but not IMAC and early changes in PMI or IMAC, were significantly associated with shorter overall survival and time to treatment failure. Conclusions: The PMI was an independent prognostic factor in UPC. Baseline muscle mass assessments may aid in risk stratification, and early nutritional or exercise interventions may benefit patients with low PMI. |
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言語 |
en |
| 出版者 |
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出版者 |
弘前大学大学院医学研究科 |
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言語 |
ja |
| 出版者 |
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出版者 |
Hirosaki University Graduate School of Medicine |
|
言語 |
en |
| 言語 |
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言語 |
jpn |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN00211444 |
| 収録物識別子 |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0439-1721 |
| 収録物識別子 |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2434-4656 |
| 書誌情報 |
ja : 弘前医学
en : Hirosaki Medical Journal
巻 76,
号 1-4,
p. 82-93,
発行日 2026-03-10
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Hirosaki Med J 76-1-4_82.pdf (1.7 MB)
