{"created":"2023-05-15T09:02:32.977634+00:00","id":3398,"links":{},"metadata":{"_buckets":{"deposit":"39a6427f-9950-4905-af80-15c354ddc50e"},"_deposit":{"created_by":3,"id":"3398","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3398"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003398","sets":["557:558:559"]},"author_link":["9610","9613","9351","9611","9355"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-12-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"321","bibliographicPageStart":"309","bibliographicVolumeNumber":"32","bibliographic_titles":[{"bibliographic_title":"Congenital Anomalies"}]}]},"item_3_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The incidences of various complications during pregnancy are not significantly\ndifferent between epileptic and nonepileptic mothers in the majority of papers\nso far reported. More than 70 to 80010 of women with epilepsy will have no change in\nseizure frequency, while 5010 will have fewer seizures than before and the remaining patients\nwill have more seizures during pregnancy provided that their drug compliance is\ngood. Intrauterine growth, in particular, of head circumference of fetus is delayed.\nHowever, this retardation disappears within few years after birth. The risk of congenital\nmalformations of the offspring born to treated epileptic mothers is greater than in\nthe general population. Among risk factors for teratogenesis that had been considered\nto date, only antiepileptic drug (AED)-related factors had proved to be significantly related\nto the occurrence of malformations. Among AEDs, methylphenobarbital, valproate,\nprimidone, carbamazepine and phenytoin are teratogenic, particularly when they are\nused in combination. Follow up EEG of children born to epileptic mothers revealed that\nthe incidence of abnormal EEG was 44010, and 28 to 38010 showed epileptiform patterns.\nOnly 7010 of offspring had epileptic seizures. In the offspring without clinical seizures\nrevealed that most of the epileptiform patterns disappear after the age 10. Recommendations\nconcerning AED therapy during pregnancy are also discussed.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Congenital Anomalies. 32(4), 1992,  p.309-321","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9611","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ナカネ, ヨシブミ"}]},{"nameIdentifiers":[{"nameIdentifier":"9355","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カネコ, スナオ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9613","nameIdentifierScheme":"WEKO"}],"names":[{"name":"中根, 充文"}]},{"nameIdentifiers":[{"nameIdentifier":"9351","nameIdentifierScheme":"WEKO"}],"names":[{"name":"兼子, 直"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本先天異常学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_relation_46":{"attribute_name":"異版である","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/110002786721","subitem_relation_type_select":"URI"}}]},"item_3_rights_14":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本先天異常学会"},{"subitem_rights":"本文データは学協会の許諾に基づきCiNiiから複製したものである"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10066760","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-3505","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"493.7","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"内科系臨床医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Neuropsychiatry, Nagasaki University School of Medicine"},{"subitem_text_value":"Department of Neuropsychiatry, Hirosaki University School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakane, Yoshibumi"}],"nameIdentifiers":[{"nameIdentifier":"9610","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kaneko, Sunao"}],"nameIdentifiers":[{"nameIdentifier":"9351","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"CongAnom_32_309.pdf","filesize":[{"value":"749.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"CongAnom_32_309.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3398/files/CongAnom_32_309.pdf"},"version_id":"4fc2fae4-8d67-471c-8012-085fae36673e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"epilepys","subitem_subject_scheme":"Other"},{"subitem_subject":"malformation","subitem_subject_scheme":"Other"},{"subitem_subject":"congenital anomaly","subitem_subject_scheme":"Other"},{"subitem_subject":"pregnancy","subitem_subject_scheme":"Other"},{"subitem_subject":"antiepileptic drug","subitem_subject_scheme":"Other"},{"subitem_subject":"facial cleft","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Congenital Anomalies in the Offspring of Epileptic Mothers","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Congenital Anomalies in the Offspring of Epileptic Mothers"}]},"item_type_id":"3","owner":"3","path":["559"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-07-17"},"publish_date":"2009-07-17","publish_status":"0","recid":"3398","relation_version_is_last":true,"title":["Congenital Anomalies in the Offspring of Epileptic Mothers"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T09:49:05.529461+00:00"}