{"created":"2023-05-15T09:02:33.556017+00:00","id":3411,"links":{},"metadata":{"_buckets":{"deposit":"0cd93903-71aa-413f-bcb0-5adc58aa17eb"},"_deposit":{"created_by":3,"id":"3411","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3411"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003411","sets":["557:558:559"]},"author_link":["9401","9866","9374","9360","9804","9373","9369","9356","9351","9844","9371","9872","9355","9368","9861","9352","9874","9359"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Multiple components of hippocampal release of neurotransmitter and modulator require the Ca²⁺ influx through specific subtypes of voltage-sensitive Ca²⁺ channel"}]},"item_3_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"シンケイ デンタツ ブッシツ シンケイ シュウショク ブッシツ ユウリ キコウ ニ タイスル デンイ イゾンセイ カルシウム イオン チャネル ノ チョウセイ キノウ"}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"260","bibliographicPageStart":"246","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"精神薬療基金研究年報"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ラット海馬におけるdopamine,serotonin,glutamate,\nadenosine遊離に対する電位依存性Ca²⁺チャネル(VSCC)の効果をin vivo microdialysis及びin vivo microdialysis glutamate biosensorを用いて検討した.Dopamine,serotoninの基礎遊離,Ca²⁺依存性遊離はN-typeVSCCに規定され,K⁺依存性遊離はP/Q-typeVSCCに規定されていた.AdenosineのCa²⁺依存性遊離はN-typeVSCCに規定され,K⁺依存性遊離はP/Q-typeVSCCに規定されていたが,基礎遊離はVSCC非感受性であった.Glutamate遊離は基礎遊離及びCa²⁺依存性遊離はVSCC非感受性であったが,K⁺依存性遊離は一過性初期増加相,後期緩徐増加相,後期多相性増加相群の3相により構成されていた.一過性初期増加相,緩徐増加相はP/Q-typeVSCCに規定されていた.spreading depressionにより生じる後期多相性増加相群はVSCC非感受性であった.これらの結果から,神経伝達物質遊離には個々の伝達物質に特異的な遊離機構が存在し,その遊離も複数の過程から構成されていることが示唆される.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"精神薬療基金研究年報. 31, 1999, p.246-260","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9355","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カネコ, スナオ"}]},{"nameIdentifiers":[{"nameIdentifier":"9401","nameIdentifierScheme":"WEKO"}],"names":[{"name":"オカダ, モトヒロ"}]},{"nameIdentifiers":[{"nameIdentifier":"9866","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ムラカミ, タクヤ"}]},{"nameIdentifiers":[{"nameIdentifier":"9844","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カワタ, ユウコ"}]},{"nameIdentifiers":[{"nameIdentifier":"9804","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ミズノ, 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Kazumaru"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"精神神経系薬物治療研究基金"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_rights_14":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"本文データは財団法人先進医薬研究振興財団の許諾に基づき複製したものである。"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00128340","subitem_source_identifier_type":"NCID"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"493.7","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"内科系臨床医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"弘前大学医学部神経精神医学講座"},{"subitem_text_value":"弘前大学医学部神経精神医学講座"},{"subitem_text_value":"弘前大学医学部神経精神医学講座"},{"subitem_text_value":"弘前大学医学部神経精神医学講座"},{"subitem_text_value":"弘前大学医学部神経精神医学講座"},{"subitem_text_value":"弘前大学医学部神経精神医学講座"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"兼子, 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depression","subitem_subject_scheme":"Other"},{"subitem_subject":"exocytosis","subitem_subject_scheme":"Other"},{"subitem_subject":"glutamate","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"神経伝達物質,神経修飾物質遊離機構に対する電位依存性カルシウムイオンチャネルの調整機能","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"神経伝達物質,神経修飾物質遊離機構に対する電位依存性カルシウムイオンチャネルの調整機能"}]},"item_type_id":"3","owner":"3","path":["559"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-11-10"},"publish_date":"2010-11-10","publish_status":"0","recid":"3411","relation_version_is_last":true,"title":["神経伝達物質,神経修飾物質遊離機構に対する電位依存性カルシウムイオンチャネルの調整機能"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:33:36.939499+00:00"}