{"created":"2023-05-15T09:02:41.465317+00:00","id":3555,"links":{},"metadata":{"_buckets":{"deposit":"aaeef9e1-40a8-45c7-9329-a56758edcef9"},"_deposit":{"created_by":3,"id":"3555","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3555"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003555","sets":["557:561:629"]},"author_link":["9620","10869","10867","9624","10865","9629"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"<総説>松果体と消化器との関連 : 消化器系におけるメラトニンの生理学的・病態生理学的意義"}]},"item_3_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"ソウセツ ショウカタイ ト ショウカキ トノ カンレン : ショウカキケイ ニオケル メラトニン ノ セイリガクテキ ビョウタイ セイリガクテキ イギ"}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-06-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3/4","bibliographicPageEnd":"108","bibliographicPageStart":"93","bibliographicVolumeNumber":"51","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Since the pineal hormone, melatonin, has been found also in the gut, pineal-digestive organ relations were\nreviewed mainly in relation to physiological and pathophysiological significance of melatonin. Melatonin is transferred\nfrom the blood into the saliva and from the intestinal lumen into the blood. Other surveyed subjects include: 1.\nContents, synthesis and receptors of melatonin in different regions of the digestive tract, its metabolism in the liver\nand their changes by various conditions; 2. Effects of melatonin or pinealectomy on structures, development, and\nfunctions of various organs in the digestive system, and preventive effects of melatonin on experimental lesions including\ngastric ulcer, ulcerative colitis, diabetes mellitus and organ transplantations. These subjects, including mechanisms\nof melatonin actions, were discussed. The gastrointestinal tract appears to have a dual system of control by melatonin:\nlocal control by paracrine or autocrine secretion from gastroenterochromaffin cells and circadian rhythmic control\nfrom the pineal. It is likely that melatonin-digestive organ relations are implicated in the adaptive-defensive mechanism\nby which the body copes with internal and external environmental factors like not only light-dark and oxidative\nstress but also temperature, water, food and activity of microorganisms, etc. relating to the light-dark environment.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 51(3/4), 2000, p.93-108","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9620","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カチ, タカシ"}]},{"nameIdentifiers":[{"nameIdentifier":"10867","nameIdentifierScheme":"WEKO"}],"names":[{"name":"クルシマ, ミチヒロ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9624","nameIdentifierScheme":"WEKO"}],"names":[{"name":"加地, 隆"}]},{"nameIdentifiers":[{"nameIdentifier":"10869","nameIdentifierScheme":"WEKO"}],"names":[{"name":"久留島, 徹大"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学医学部・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"491.1","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"基礎医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"弘前大学医学部解剖学第ニ講座"},{"subitem_text_value":"弘前大学医学部解剖学第ニ講座"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kachi, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kurushima, Michihiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_51_3-4_93.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_51_3-4_93.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3555/files/HirosakiMedJ_51_3-4_93.pdf"},"version_id":"cf8f7311-184d-4442-bf32-a08d11f7eca2"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"melatonin","subitem_subject_scheme":"Other"},{"subitem_subject":"melatonin receptor","subitem_subject_scheme":"Other"},{"subitem_subject":"active oxygen","subitem_subject_scheme":"Other"},{"subitem_subject":"gastric ulcer","subitem_subject_scheme":"Other"},{"subitem_subject":"diabetes mellitus","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"<Review> Pineal-Digestive Organ Relations : Physiological and Pathophysiological Significance of Melatonin in the Digestive System","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"<Review> Pineal-Digestive Organ Relations : Physiological and Pathophysiological Significance of Melatonin in the Digestive System"}]},"item_type_id":"3","owner":"3","path":["629"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-05-26"},"publish_date":"2009-05-26","publish_status":"0","recid":"3555","relation_version_is_last":true,"title":["<Review> Pineal-Digestive Organ Relations : Physiological and Pathophysiological Significance of Melatonin in the Digestive System"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T11:08:49.151545+00:00"}