{"created":"2023-05-15T09:02:41.668774+00:00","id":3558,"links":{},"metadata":{"_buckets":{"deposit":"3674ed89-8cb3-4d9d-905b-38470f0e63ad"},"_deposit":{"created_by":3,"id":"3558","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3558"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003558","sets":["557:561:630"]},"author_link":["9401","9369","9355","9356","9351","9844","9373","9374","9352","9368"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"てんかんの遺伝子 : イオンチャネルへたどり着いた興奮"}]},"item_3_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"テンカン ノ イデンシ : イオン チャネル エ タドリツイタ コウフン"}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1999-11-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Suppl.","bibliographicPageEnd":"S105","bibliographicPageStart":"S99","bibliographicVolumeNumber":"51","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Epilepsy is a neurological disorder characterized by recurring seizures. It is physiologically\ncharacterized by abnormal, excessive and self-terminating discharges from neurons. Epilepsy affects more\nthan 0.5 % of the world's population and has a large genetic component. The most common human genetic\nepilepsies display a complex pattern of inheritance and the identity of the susceptibility genes is largely\nunknown. This article reviews recent progress made in molecular genetics of epilepsy, including our own\ndiscovery of two novel mutations in the genes of autosomal dominant nocturnal frontal lobe epilepsy and\nbenign familial neonatal convulsions, and our mapping of the genetic locus of benign adult familial myoclonic\nepilepsy. Pathogenesis of epilepsy as a channelopathy and perspectives of molecular genetic study of epilepsy\nare also discussed.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 51(Suppl.), 1999, p.S99-105","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9355","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カネコ, スナオ"}]},{"nameIdentifiers":[{"nameIdentifier":"9356","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ワダ, カズマル"}]},{"nameIdentifiers":[{"nameIdentifier":"9401","nameIdentifierScheme":"WEKO"}],"names":[{"name":"オカダ, モトヒロ"}]},{"nameIdentifiers":[{"nameIdentifier":"9844","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カワタ, ユウコ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9351","nameIdentifierScheme":"WEKO"}],"names":[{"name":"兼子, 直"}]},{"nameIdentifiers":[{"nameIdentifier":"9352","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"371","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/371_ja.html"}],"names":[{"name":"和田, 一丸"}]},{"nameIdentifiers":[{"nameIdentifier":"9368","nameIdentifierScheme":"WEKO"}],"names":[{"name":"岡田, 元宏"}]},{"nameIdentifiers":[{"nameIdentifier":"9369","nameIdentifierScheme":"WEKO"}],"names":[{"name":"河田, 祐子"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学医学部・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"493.74","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"内科系臨床医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Neuropsychiatry, Hirosaki University School of Medicine"},{"subitem_text_value":"Department of Neuropsychiatry, Hirosaki University School of Medicine"},{"subitem_text_value":"Department of Neuropsychiatry, Hirosaki University School of Medicine"},{"subitem_text_value":"Department of Neuropsychiatry, Hirosaki University School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kaneko, Sunao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Wada, Kazumaru"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Okada, Motohiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawata, Yuko"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"AN00211444_51-s_s99.pdf","filesize":[{"value":"489.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00211444_51-s_s99.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3558/files/AN00211444_51-s_s99.pdf"},"version_id":"e923a277-8859-4e9d-b971-853a97e68b18"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"epilepsy","subitem_subject_scheme":"Other"},{"subitem_subject":"genes","subitem_subject_scheme":"Other"},{"subitem_subject":"autosomal dominant nocturnal frontal lobe epilepsy","subitem_subject_scheme":"Other"},{"subitem_subject":"benign familial neonatal convulsions","subitem_subject_scheme":"Other"},{"subitem_subject":"benign adult familial myoclonic epilepsy","subitem_subject_scheme":"Other"},{"subitem_subject":"てんかん","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子","subitem_subject_scheme":"Other"},{"subitem_subject":"常染色体優性夜間性前頭葉てんかん","subitem_subject_scheme":"Other"},{"subitem_subject":"良性家族性新生児けいれん","subitem_subject_scheme":"Other"},{"subitem_subject":"良性成人型ミオクロニーてんかん","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Epilepsy Genes : Excitement Traced to Ion Channels","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Epilepsy Genes : Excitement Traced to Ion Channels"}]},"item_type_id":"3","owner":"3","path":["630"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-06-11"},"publish_date":"2009-06-11","publish_status":"0","recid":"3558","relation_version_is_last":true,"title":["Epilepsy Genes : Excitement Traced to Ion Channels"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:46:18.239021+00:00"}