{"created":"2023-05-15T09:02:44.691310+00:00","id":3612,"links":{},"metadata":{"_buckets":{"deposit":"26de6af0-9e3e-428d-9374-0d79f5fcc0bf"},"_deposit":{"created_by":3,"id":"3612","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3612"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003612","sets":["557:561:642"]},"author_link":["11760","11129","11759","11764","11765","11750","11754","11758","11752","11138","11756","11751","11755","11761","11762","11749","11753","11121"],"item_5_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Caerulein Induced Pancreatitis and Expression of Receptor for Advanced Glycation Endproducts in Spontaneously Diabetic Torii Rat"}]},"item_5_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"Spontaneously Diabetic Torii (SDT) ラット ニオケル セルレイン ユウドウ キュウセイ フシュセイ スイエン ト Receptor for Advanced Glycation Endproducts (RAGE) ノ ハツゲン"}]},"item_5_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2/3/4","bibliographicPageEnd":"117","bibliographicPageStart":"110","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_5_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"病歴の長い糖尿病患者において,アミラーゼ分泌の低下や障萎縮･線維化を呈する症例があることが報告されている.しかしこのような病態の動物モデルは現在確立されていない.また,終末糖化産物AGE,その受容体であるRAGEは糖尿病血管合併症に関与しているとされているが,陣-の影響は不明である.糖尿病における障外分泌障害とその機序を明らかにするため,加齢により障ラ氏島の線維化を生じる自然発症2型糖尿病モデル,SpontaneouslyDiabeticTorii(SDT)ラットにcaerulein急性輝炎を発症させ,糖尿病の発症および程度,降の線維化に変化を生じるか否か,同時に,RAGEの発現をRT-PCRにより検討した.結果,障炎による糖尿病発症および降の線維化,糖尿病発症前後および輝炎の有無によるRAGEの発現に変化は認めず,糖尿病ラットモデルにおける障障害とRAGEの関連は明らかではなかった.","subitem_description_type":"Abstract"}]},"item_5_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 59, 2008, p.110-117","subitem_description_type":"Other"}]},"item_5_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11754","nameIdentifierScheme":"WEKO"}],"names":[{"name":"サトウ, エリ"}]},{"nameIdentifiers":[{"nameIdentifier":"11755","nameIdentifierScheme":"WEKO"}],"names":[{"name":"タムラ, アヤメ"}]},{"nameIdentifiers":[{"nameIdentifier":"11756","nameIdentifierScheme":"WEKO"}],"names":[{"name":"タンドウ, ユウスケ"}]},{"nameIdentifiers":[{"nameIdentifier":"11129","nameIdentifierScheme":"WEKO"}],"names":[{"name":"スダ, トシヒロ"}]},{"nameIdentifiers":[{"nameIdentifier":"11758","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ナカムラ, テルオ"}]},{"nameIdentifiers":[{"nameIdentifier":"11759","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヤマギシ, ショウイチ"}]}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11760","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"100000601","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/100000601_ja.html"}],"names":[{"name":"Sato, Eri"}]},{"nameIdentifiers":[{"nameIdentifier":"11761","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tamura, Ayame"}]},{"nameIdentifiers":[{"nameIdentifier":"11762","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"442","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/442_ja.html"}],"names":[{"name":"Tando, Yusuke"}]},{"nameIdentifiers":[{"nameIdentifier":"11138","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Suda, Toshihiro"}]},{"nameIdentifiers":[{"nameIdentifier":"11764","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakamura, 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Shoichi"}]}]},"item_5_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_5_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_5_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_5_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"493.1","subitem_subject_scheme":"NDC"}]},"item_5_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"内科系臨床医学","subitem_subject_scheme":"Other"}]},"item_5_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"弘前大学大学院医学研究科内分泌代謝内科学講座"},{"subitem_text_value":"弘前大学大学院医学研究科内分泌代謝内科学講座"},{"subitem_text_value":"弘前大学大学院医学研究科内分泌代謝内科学講座"},{"subitem_text_value":"弘前大学大学院医学研究科内分泌代謝内科学講座"},{"subitem_text_value":"弘前大学大学院保健学科"},{"subitem_text_value":"久留米大学心臓血管内科"},{"subitem_text_value":"Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Health Science, Hirosaki University School of Medicine"},{"subitem_text_value":"Division of Cardio-vascular Medicine, Kurume University School of Medicine"}]},"item_5_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 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(RAGE)の発現"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T09:43:58.258589+00:00"}