{"created":"2023-05-15T09:02:44.779285+00:00","id":3614,"links":{},"metadata":{"_buckets":{"deposit":"e1bcd3a7-35c5-460b-8c33-dfd0e7496cf5"},"_deposit":{"created_by":3,"id":"3614","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3614"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003614","sets":["557:561:642"]},"author_link":["11787","11794","11788","11784","11789","11786","11790","11792","11791","11795","11785","11782","11781","11793","11783"],"item_5_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"妊娠高血圧症候群胎盤の絨毛間腔におけるプロテオグリカン発現やグリコサミノグリカン構造の変化"}]},"item_5_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"ニンプ コウケツアツ ショウコウグン タイバン ノ ジュモウ カンクウ ニオケル プロテオグリカン ハツゲン ヤ グリコサミノグリカン コウゾウ ノ ヘンカ"}]},"item_5_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2/3/4","bibliographicPageEnd":"135","bibliographicPageStart":"128","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_5_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_5_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The changes in proteoglycan (PG) expression and glycosaminoglycan (GAG) constituents in the intervillous space of the pregnancy-induced hypertension (PIR) placenta were investigated. PGs and GAGs were purified from the extract of the placental intervillous space by the DEAE-Sephacel column and salt-concentration gradient method. and the GAG sugar chains were released by the actinase and cellulase treatments. The sugar chains from the placentas of normal pregnancy and PIR were compared by cellulose-acetate membrane electrophoresis. No difference was observed in the expressions of hyaluronic acid. heparan sulfate, and chondroitin sulfate. but a clear increase in the expression of dermatan sulfate (DS) in the placenta of the PIR was confirmed. An increase of the DS that specifically activates anticoagulants can be a body reaction to counteract the hemostatic condition observed in PIR.","subitem_description_type":"Abstract"}]},"item_5_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 59, 2008, p.128-135","subitem_description_type":"Other"}]},"item_5_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11786","nameIdentifierScheme":"WEKO"}],"names":[{"name":"マツクラ, ダイスケ"}]},{"nameIdentifiers":[{"nameIdentifier":"11787","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヨコヤマ, ヨシヒト"}]},{"nameIdentifiers":[{"nameIdentifier":"11788","nameIdentifierScheme":"WEKO"}],"names":[{"name":"タナカ, カンジ"}]},{"nameIdentifiers":[{"nameIdentifier":"11789","nameIdentifierScheme":"WEKO"}],"names":[{"name":"オザキ, タカシ"}]},{"nameIdentifiers":[{"nameIdentifier":"11790","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ミズヌマ, ヒデキ"}]}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11791","nameIdentifierScheme":"WEKO"}],"names":[{"name":"松倉, 大輔"}]},{"nameIdentifiers":[{"nameIdentifier":"11792","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"291","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/291_ja.html"}],"names":[{"name":"横山, 良仁"}]},{"nameIdentifiers":[{"nameIdentifier":"11793","nameIdentifierScheme":"WEKO"}],"names":[{"name":"田中, 幹ニ"}]},{"nameIdentifiers":[{"nameIdentifier":"11794","nameIdentifierScheme":"WEKO"}],"names":[{"name":"尾崎, 浩士"}]},{"nameIdentifiers":[{"nameIdentifier":"11795","nameIdentifierScheme":"WEKO"}],"names":[{"name":"水沼, 英樹"}]}]},"item_5_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_5_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_5_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_5_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"495.6","subitem_subject_scheme":"NDC"}]},"item_5_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"外科系臨床医学","subitem_subject_scheme":"Other"}]},"item_5_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Obstetrics and Gynecology, Hirosaki University School of Medicine"},{"subitem_text_value":"Department of Obstetrics and Gynecology, Hirosaki University School of Medicine"},{"subitem_text_value":"Department of Obstetrics and Gynecology, Hirosaki University School of Medicine"},{"subitem_text_value":"Department of Obstetrics and Gynecology, Hirosaki University School of Medicine"},{"subitem_text_value":"Department of Obstetrics and Gynecology, Hirosaki University School of Medicine"},{"subitem_text_value":"弘前大学医学部産科婦人科学講座"},{"subitem_text_value":"弘前大学医学部産科婦人科学講座"},{"subitem_text_value":"弘前大学医学部産科婦人科学講座"},{"subitem_text_value":"弘前大学医学部産科婦人科学講座"},{"subitem_text_value":"弘前大学医学部産科婦人科学講座"}]},"item_5_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Matsukura, Daisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yokoyama, Yoshihito"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Tanaka, Kanji"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Ozaki, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mizunuma, Hideki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"AN00211444_59_128.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00211444_59_128.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3614/files/AN00211444_59_128.pdf"},"version_id":"68122958-9e7e-46ff-a684-422353c49985"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"proteoglycans","subitem_subject_scheme":"Other"},{"subitem_subject":"glycosaminoglycans","subitem_subject_scheme":"Other"},{"subitem_subject":"pregnancy-induced hypertension","subitem_subject_scheme":"Other"},{"subitem_subject":"placenta","subitem_subject_scheme":"Other"},{"subitem_subject":"dermatan sulfate","subitem_subject_scheme":"Other"},{"subitem_subject":"プロテオグリカン","subitem_subject_scheme":"Other"},{"subitem_subject":"グリコサミノグリカン","subitem_subject_scheme":"Other"},{"subitem_subject":"妊娠高血圧症候群","subitem_subject_scheme":"Other"},{"subitem_subject":"胎盤","subitem_subject_scheme":"Other"},{"subitem_subject":"デルマタン硫酸","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Changes of Proteoglycan Expression and Glycosaminoglycan Constituents in the Intervillous Space of the Pregnancy-Induced Hypertension Placenta","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Changes of Proteoglycan Expression and Glycosaminoglycan Constituents in the Intervillous Space of the Pregnancy-Induced Hypertension Placenta"}]},"item_type_id":"5","owner":"3","path":["642"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-08-21"},"publish_date":"2008-08-21","publish_status":"0","recid":"3614","relation_version_is_last":true,"title":["Changes of Proteoglycan Expression and Glycosaminoglycan Constituents in the Intervillous Space of the Pregnancy-Induced Hypertension Placenta"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:06:01.438055+00:00"}