{"created":"2023-05-15T09:02:45.946819+00:00","id":3632,"links":{},"metadata":{"_buckets":{"deposit":"52bf1093-a3e4-4823-b53a-d6b39c5b051a"},"_deposit":{"created_by":3,"id":"3632","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3632"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003632","sets":["557:561:643"]},"author_link":["11858","11859","11857","11860","11861"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-11-29","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Supplement","bibliographicPageEnd":"S136","bibliographicPageStart":"S128","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"To investigated the eff ect of high volume continuous hemofi ltration（ HVHF） on the lung lesion observed\nwith transesophageal echocardiography （TEE） in endotoxin-induced acute lung injury in piglets. Piglets weighing\n20-30kg. Interventions: After endotoxin of 20 μg/kg intravenous administration, animals were randomly assigned to\ncontrol group（ n=7） and HVHF group（ n=7）. In both group, fi ltration was performed for fi ve hours and zero balanced.\nFiltration fl ow was 150 ml/hr in HVHF group and 0ml/hr in control group. The area of the lesion, resistive index\nand maximal blood velocity in regional pulmonary artery were estimated using TEE. High mobility group B1 protein\n（HMGB1）, cortisol and catecholamine concentrations were measured in plasma at endotoxin 5 hours. Measurements of\nblood gas, hemodynamics and TEE images were obtained every hour. The value of PaO2, density area and resistive\nindex were 70.0±8.8 mmHg, 10.7±4.5 cm2 and 0.61±0.23 in control group and 120.4±20.3 mmHg, 3.3±2.0 cm2 and 0.88\n±0.22 in HVHF group at endotoxin 5 hours respectively（ mean±SD）. PaO2 and resistive index increased, and density\narea decreased in HVHF group than those of control group signifi cantly（ p<0.05, respectively）. There was signifi cant\nrelationship between PaO2 and density area （r=0.76, p<0.01）. There was no signifi cant diff erence in hemodynamics,\nHMGB1, cortisol and catecholamines concentration in plasma and morphometry between control group and HVHF\ngroup. In conclusion, these results suggest that non-specifi c blood purifi cation with HVHF improves arterial oxygenation\nand lung image observed with TEE in endotoxin-induced acute lung injury in piglets.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 59(Suppl.), 2007, p.S128-S136","subitem_description_type":"Other"}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"492.8","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Intensive Care Unit and Department of Anesthesiology, University of Hirosaki, Graduate School of Medicine"},{"subitem_text_value":"Intensive Care Unit and Department of Anesthesiology, University of Hirosaki, Graduate School of Medicine"},{"subitem_text_value":"Intensive Care Unit and Department of Anesthesiology, University of Hirosaki, Graduate School of Medicine"},{"subitem_text_value":"Intensive Care Unit and Department of Anesthesiology, University of Hirosaki, Graduate School of Medicine"},{"subitem_text_value":"Intensive Care Unit and Department of Anesthesiology, University of Hirosaki, Graduate School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tsubo, Toshihito"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujita, Ayaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hashiba, Eiji"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Ishihara, Hironori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hirota, Kazuyoshi"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_59_S128.pdf","filesize":[{"value":"907.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_59_S128.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3632/files/HirosakiMedJ_59_S128.pdf"},"version_id":"e2bd980f-60f8-42cc-b9b9-e8be304ed71b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Continuous venovenous hemofi ltration improves endotoxin induced lung injury in pigs : Evaluation with ultrasonography","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Continuous venovenous hemofi ltration improves endotoxin induced lung injury in pigs : Evaluation with ultrasonography"}]},"item_type_id":"3","owner":"3","path":["643"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-09-18"},"publish_date":"2009-09-18","publish_status":"0","recid":"3632","relation_version_is_last":true,"title":["Continuous venovenous hemofi ltration improves endotoxin induced lung injury in pigs : Evaluation with ultrasonography"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:01:35.757815+00:00"}