{"created":"2023-05-15T09:02:46.723163+00:00","id":3649,"links":{},"metadata":{"_buckets":{"deposit":"247012fd-ec41-45cd-8923-3a5bc91005b9"},"_deposit":{"created_by":3,"id":"3649","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3649"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003649","sets":["557:561:643"]},"author_link":["9620","9624","9629"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-11-29","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Suppl.","bibliographicPageEnd":"S277","bibliographicPageStart":"S262","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_17":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Various aspects of pineal structures and functions have been reviewed. mainly relating to our own\nobservations and experiments. The pineal gland shows high amplitude circadian rhythms in cellular and metabolic\nactivities. which are changeable under various circumstances. The pineal hormone appears to participate in the body's\nadaptive regulatory system mostly by cooperative and modulatory mechanisms. particularly in relation to environmental\nchanges including stress/invasion. timing of physiological processes including reproductive activities. and possibly\nexogenous and endogenous pathological changes such as inflammatory disease and tumor. Pineal effects are variable\ndue to the sensitivity/state of target mechanisms. For example. the pinealectomy effects on adreno-medullary adrenaline\ncells were more evident in comparison with the 'sham-pinealectomy' group than the normal group, and the pinealectomy\neffects on female reproductive activities were age-dependent. In any case, the pineal hormone retains physiological\nfunctions at least till middle age. Pineal actions are mainly inhibitory. but can be also stimulatory as shown in immune\nregulatory mechanisms. It has long been known that big differences in pineal structures and functions exist between\nmammals and submammals and that mammals show characteristic development of the brain, autonomic nervous system\nand unique style of reproduction including pregnancy and suckling. These and other related results seem to support a\nhypothetical view that the pineal hormone was involved in drastic reorganization of the regulatory system occurred in\nthe evolutional process from submammals to mammals and became participated in the system which regulates complex\nbody mechanisms in mammals.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 59(Suppl.), 2007, p.S262-277","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9620","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カチ, タカシ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"9624","nameIdentifierScheme":"WEKO"}],"names":[{"name":"加地, 隆"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"491.1","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"基礎医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Anatomical Science, Hirosaki University Graduate School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kachi, Takashi"}],"nameIdentifiers":[{"nameIdentifier":"9629","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_59_S262.pdf","filesize":[{"value":"376.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_59_S262.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3649/files/HirosakiMedJ_59_S262.pdf"},"version_id":"718b225b-a6c1-4074-a84c-5561f8220fc0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"chronobiology","subitem_subject_scheme":"Other"},{"subitem_subject":"stress","subitem_subject_scheme":"Other"},{"subitem_subject":"female reproductive activity","subitem_subject_scheme":"Other"},{"subitem_subject":"immune mechanism","subitem_subject_scheme":"Other"},{"subitem_subject":"pathology","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Pineal Structures and Functions in Mammalian Body Mechanisms Coping with Exogenous and Endogenous Changes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Pineal Structures and Functions in Mammalian Body Mechanisms Coping with Exogenous and Endogenous Changes"}]},"item_type_id":"3","owner":"3","path":["643"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-05-26"},"publish_date":"2009-05-26","publish_status":"0","recid":"3649","relation_version_is_last":true,"title":["Pineal Structures and Functions in Mammalian Body Mechanisms Coping with Exogenous and Endogenous Changes"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T11:08:59.491338+00:00"}