{"created":"2023-05-15T09:02:48.028570+00:00","id":3674,"links":{},"metadata":{"_buckets":{"deposit":"bc01f87d-b497-42c9-a22a-f0043ea6ab58"},"_deposit":{"created_by":3,"id":"3674","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3674"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003674","sets":["557:561:646"]},"author_link":["12273","11242","12263","12267","12269","12271","11238","12275","11790","12260","12261","12265","11246","12264","11785","11795","12270","12262"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"機能的糖鎖の変化からみた骨粗鬆症病態の解明"}]},"item_3_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"キノウテキ トウサ ノ ヘンカ カラミタ コツソショウショウ ビョウタイ ノ カイメイ"}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-01-17","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-4","bibliographicPageEnd":"103","bibliographicPageStart":"97","bibliographicVolumeNumber":"61","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of study is to analyze functional sugar chains, glycosaminoglycans （GAGs） in urine from\npostmenopausal women with osteoporosis. A 24-hour urine was collected from 15 osteoporotic women and normal\nwomen. All women were postmenopausal and aged at 60 to 70 years old. Diagnosis of osteoporosis was based on\nthe diagnosis criteria proposed by the Japan Osteoporosis Society after measurement of lumbar spine bone mineral\ndensity by dual energy X-ray absorptiometry. The urine was concentrated by dialysis and evaporation, then\nprecipitated with ethanol. The precipitate was then reconstituted into NaCl solution, precipitated again by adding 10% cetylpyridinium chloride and the precipitation was used as complex GAGs fraction. The yield of complex fraction\nwas significantly higher in osteoporotic subjects than that in normal control. Then, the complex GAGs fraction was\nanalyzed by cellulose acetate membrane electrophoresis and high performance liquid chromatography （HPLC）,\nrespectively. Cellulose acetate membrane electrophoresis has revealed that GAGs in urine contained partially\ndesulfated chondroitin sulfate. However, further analysis by HPLC has shown that the excretion of desulfated GAGs\nwas rather less in osteoporotic women, indicating that urinary GAGs fraction from osteoporotic women contains\nunknown acidic polysaccharides as well as GAGs.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 61(2-4), 2011, p.97-103","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"12264","nameIdentifierScheme":"WEKO"}],"names":[{"name":"アベ, カズヒロ"}]},{"nameIdentifiers":[{"nameIdentifier":"12265","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヒグチ, ツヨシ"}]},{"nameIdentifiers":[{"nameIdentifier":"11790","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ミズヌマ, ヒデキ"}]},{"nameIdentifiers":[{"nameIdentifier":"12267","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カキザキ, イクコ"}]},{"nameIdentifiers":[{"nameIdentifier":"11246","nameIdentifierScheme":"WEKO"}],"names":[{"name":"エンドウ, マサヒコ"}]},{"nameIdentifiers":[{"nameIdentifier":"12269","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ストウ, シンイチロウ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"12270","nameIdentifierScheme":"WEKO"}],"names":[{"name":"阿部, 和弘"}]},{"nameIdentifiers":[{"nameIdentifier":"12271","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"511","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/511_ja.html"}],"names":[{"name":"樋口, 毅"}]},{"nameIdentifiers":[{"nameIdentifier":"11795","nameIdentifierScheme":"WEKO"}],"names":[{"name":"水沼, 英樹"}]},{"nameIdentifiers":[{"nameIdentifier":"12273","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"196","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/196_ja.html"}],"names":[{"name":"柿崎, 育子"}]},{"nameIdentifiers":[{"nameIdentifier":"11242","nameIdentifierScheme":"WEKO"}],"names":[{"name":"遠藤, 正彦"}]},{"nameIdentifiers":[{"nameIdentifier":"12275","nameIdentifierScheme":"WEKO"}],"names":[{"name":"須藤, 晋一郎"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"493.6","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"内科系臨床医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Obstetrics and Gynecology, Graduate School of Medicine, Hirosaki University"},{"subitem_text_value":"Department of Obstetrics and Gynecology, Graduate School of Medicine, Hirosaki University"},{"subitem_text_value":"Department of Obstetrics and Gynecology, Graduate School of Medicine, Hirosaki University"},{"subitem_text_value":"Department of Glycotechnology, Center for Advanced Medical Research, Graduate School of Medicine, Hirosaki University"},{"subitem_text_value":"Department of Glycotechnology, Center for Advanced Medical Research, Graduate School of Medicine, Hirosaki University"},{"subitem_text_value":"Department of Glycomedicine, Center for Advanced Medical Research, Graduate School of Medicine, Hirosaki University"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Abe, Kazuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Higuchi, Tsuyoshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Mizunuma, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kakizaki, Ikuko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Endo, Masahiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suto, Shinichiro"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_61(2-4)_97.pdf","filesize":[{"value":"201.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_61(2-4)_97.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3674/files/HirosakiMedJ_61(2-4)_97.pdf"},"version_id":"fd3b93e8-6457-48e3-aaa0-a84651ef5c37"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Osteoporosis","subitem_subject_scheme":"Other"},{"subitem_subject":"Urine","subitem_subject_scheme":"Other"},{"subitem_subject":"Glycosaminoglycan","subitem_subject_scheme":"Other"},{"subitem_subject":"骨粗鬆症","subitem_subject_scheme":"Other"},{"subitem_subject":"尿","subitem_subject_scheme":"Other"},{"subitem_subject":"グリコサミノグリカン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ANALYSIS OF FUNCTIONAL SUGAR CHAINS OF PROTEOGLYCANS IN THE URINE FROM WOMEN WITH OSTEOPOROSIS","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ANALYSIS OF FUNCTIONAL SUGAR CHAINS OF PROTEOGLYCANS IN THE URINE FROM WOMEN WITH OSTEOPOROSIS"}]},"item_type_id":"3","owner":"3","path":["646"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-01-24"},"publish_date":"2011-01-24","publish_status":"0","recid":"3674","relation_version_is_last":true,"title":["ANALYSIS OF FUNCTIONAL SUGAR CHAINS OF PROTEOGLYCANS IN THE URINE FROM WOMEN WITH OSTEOPOROSIS"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:06:03.598149+00:00"}