{"created":"2023-05-15T09:02:49.894895+00:00","id":3715,"links":{},"metadata":{"_buckets":{"deposit":"f2716a08-8968-4012-8a07-41b29cbef3fd"},"_deposit":{"created_by":3,"id":"3715","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3715"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003715","sets":["557:561:647"]},"author_link":["13459","12570","12643","12640","12634","12562","13471","12636","12641","12638","12639","13458","12637","12565"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-07-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Supplement","bibliographicPageEnd":"S254","bibliographicPageStart":"S252","bibliographicVolumeNumber":"61","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　Although animal studies suggest that centrally active angiotensin-converting enzyme （ACE） inhibitors may protect against dementia beyond HTN control, the mechanism（s） underlying these improvements in cognitive function remains unclear. We measured the brain peptide levels in rat treated with captopril（ 50 mg/kg） for 3 weeks by using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry （SELDI TOF-MS）. Two protein chip arrays were used for peptide profi ling： one with a strong anion- exchanger and the other with a weak cation-exchanger.\n　Comparing with control group, 15 mass peaks were considered specifi c to experimental animals, and 6 peaks were signifi cantly up-regulated and 5 down-regulated.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 61(Suppl.), 2010, p.S252-S254","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"12638","nameIdentifierScheme":"WEKO"}],"names":[{"name":"マルヤマ, アユミ"}]},{"nameIdentifiers":[{"nameIdentifier":"12639","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カナザワ, サチコ"}]},{"nameIdentifiers":[{"nameIdentifier":"12640","nameIdentifierScheme":"WEKO"}],"names":[{"name":"シモヤマ, リツコ"}]},{"nameIdentifiers":[{"nameIdentifier":"12641","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ホソイ, カズヒロ"}]},{"nameIdentifiers":[{"nameIdentifier":"12565","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ハヤカリ, マコト"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"13458","nameIdentifierScheme":"WEKO"}],"names":[{"name":"金澤, 佐知子"}]},{"nameIdentifiers":[{"nameIdentifier":"12643","nameIdentifierScheme":"WEKO"}],"names":[{"name":"下山, 律子"}]},{"nameIdentifiers":[{"nameIdentifier":"13459","nameIdentifierScheme":"WEKO"}],"names":[{"name":"細井, 一広"}]},{"nameIdentifiers":[{"nameIdentifier":"12570","nameIdentifierScheme":"WEKO"}],"names":[{"name":"早狩, 誠"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Pharmacy, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacy, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacy, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacy, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacy, Hirosaki University Graduate School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Maruyama, Ayumi"}],"nameIdentifiers":[{"nameIdentifier":"12634","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanazawa, Sachiko"}],"nameIdentifiers":[{"nameIdentifier":"13471","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shimoyama, Ritsuko"}],"nameIdentifiers":[{"nameIdentifier":"12636","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hosoi, Kazuhiro"}],"nameIdentifiers":[{"nameIdentifier":"12637","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hayakari, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"12562","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_61_S252.pdf","filesize":[{"value":"115.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_61_S252.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3715/files/HirosakiMedJ_61_S252.pdf"},"version_id":"a9da4577-137f-4ad2-8708-c05b6d98af4a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ACE inhibitors","subitem_subject_scheme":"Other"},{"subitem_subject":"captopril","subitem_subject_scheme":"Other"},{"subitem_subject":"memory","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"＜Poster＞Alteration of peptides in rat brain treated with angiotensin-converting enzyme Inhibitor, captopril","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"＜Poster＞Alteration of peptides in rat brain treated with angiotensin-converting enzyme Inhibitor, captopril"}]},"item_type_id":"3","owner":"3","path":["647"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-08-19"},"publish_date":"2010-08-19","publish_status":"0","recid":"3715","relation_version_is_last":true,"title":["＜Poster＞Alteration of peptides in rat brain treated with angiotensin-converting enzyme Inhibitor, captopril"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:45:20.692630+00:00"}