{"created":"2023-05-15T09:02:51.570185+00:00","id":3746,"links":{},"metadata":{"_buckets":{"deposit":"256d58a8-c7ba-40c0-9962-7f521a1868a6"},"_deposit":{"created_by":3,"id":"3746","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3746"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003746","sets":["557:561:651"]},"author_link":["13248","13244","12691","13252","12253","13253","12259","12244","12245","12251","13246","12713","13258","13241","13262","12238","11855","12252","12237","12255","13264","12246","12701","12240","13254","13245","13263","12247","12239","12254"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"生体内必須微量元素が好中球の活性酸素種産生量に及ぼす影響"}]},"item_3_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"セイタイナイ ヒッス ビリョウ ゲンソ ガ コウチュウキュウ ノ カッセイ サンソシュ セイサンリョウ ニ オヨボス エイキョウ"}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-11-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-4","bibliographicPageEnd":"95","bibliographicPageStart":"85","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: We investigated the relationship between trace element concentrations and neutrophil basalreactive oxygen species（ ROS） production capability among the Japanese general population.\n　 Subjects and methods: Subjects of the current study were 606 participants（ 225 males and 381 females） who had participated in the Iwaki Health Promotion Project 2005. Body mass index, biochemical blood examination, neutrophil\nbasal ROS production and serum concentrations of trace element （Copper（Cu）, Zinc（Zn）, Iron（Fe）, Selenium\n（Se）） were measured. Each trace element was divided into 4 quartiles according to the concentration, and the\nneutrophil basal ROS production of each group was compared and analyzed. Moreover, the relationship between the concentration and neutrophil basal ROS production capability was assessed using a multiple linear regression analysis.\n　 Results: For both males and females, a tendency to low neutrophil ROS production associated with higher Se serum concentration was observed. On the other hand, no significant correlation was observed between the Cu, Zn and Fe concentrations and neutrophil basal ROS production capability.\n　 Conclusion: In conclusion, serum Se relieves oxidative stress through inhibiting neutrophil ROS production within a physiological range. On the other hand, our results suggested that neutrophil ROS production was unaffected by Cu, Zn and Fe concentrations within the normal physiological range.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 63, 2012, p.85-95","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"13248","nameIdentifierScheme":"WEKO"}],"names":[{"name":"イトウ, ハルユキ"}]},{"nameIdentifiers":[{"nameIdentifier":"12246","nameIdentifierScheme":"WEKO"}],"names":[{"name":"タカハシ, イッペイ"}]},{"nameIdentifiers":[{"nameIdentifier":"12247","nameIdentifierScheme":"WEKO"}],"names":[{"name":"マツザカ, マサシ"}]},{"nameIdentifiers":[{"nameIdentifier":"12244","nameIdentifierScheme":"WEKO"}],"names":[{"name":"イ, サンユン"}]},{"nameIdentifiers":[{"nameIdentifier":"13252","nameIdentifierScheme":"WEKO"}],"names":[{"name":"サカイ, カズヨシ"}]},{"nameIdentifiers":[{"nameIdentifier":"13253","nameIdentifierScheme":"WEKO"}],"names":[{"name":"フクイ, シンジ"}]},{"nameIdentifiers":[{"nameIdentifier":"13254","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ハマダ, ナオコ"}]},{"nameIdentifiers":[{"nameIdentifier":"12701","nameIdentifierScheme":"WEKO"}],"names":[{"name":"サイトウ, ユリコ"}]},{"nameIdentifiers":[{"nameIdentifier":"12245","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ウメダ, タカシ"}]},{"nameIdentifiers":[{"nameIdentifier":"12251","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ナカジ, シゲユキ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"13258","nameIdentifierScheme":"WEKO"}],"names":[{"name":"伊藤, 治幸"}]},{"nameIdentifiers":[{"nameIdentifier":"12254","nameIdentifierScheme":"WEKO"}],"names":[{"name":"高橋, 一平"}]},{"nameIdentifiers":[{"nameIdentifier":"12255","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"220","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/220_ja.html"}],"names":[{"name":"松坂, 方士"}]},{"nameIdentifiers":[{"nameIdentifier":"12252","nameIdentifierScheme":"WEKO"}],"names":[{"name":"李, 相潤"}]},{"nameIdentifiers":[{"nameIdentifier":"13262","nameIdentifierScheme":"WEKO"}],"names":[{"name":"板井, 一好"}]},{"nameIdentifiers":[{"nameIdentifier":"13263","nameIdentifierScheme":"WEKO"}],"names":[{"name":"福井, 真司"}]},{"nameIdentifiers":[{"nameIdentifier":"13264","nameIdentifierScheme":"WEKO"}],"names":[{"name":"浜田, 菜穂子"}]},{"nameIdentifiers":[{"nameIdentifier":"12713","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"200000122","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/200000122_ja.html"}],"names":[{"name":"齋藤, 百合子"}]},{"nameIdentifiers":[{"nameIdentifier":"12253","nameIdentifierScheme":"WEKO"}],"names":[{"name":"梅田, 孝"}]},{"nameIdentifiers":[{"nameIdentifier":"12259","nameIdentifierScheme":"WEKO"}],"names":[{"name":"中路, 重之"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"基礎医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"弘前大学大学院医学研究科社会医学"},{"subitem_text_value":"青森県立保健大学健康科学部"},{"subitem_text_value":"岩手医科大学医学部衛生学公衆衛生学"},{"subitem_text_value":"尚絅学院大学"},{"subitem_text_value":"防衛医科大学校高等看護学院"},{"subitem_text_value":"弘前大学大学院医学研究科形成外科学"},{"subitem_text_value":"Department of Social Medicine, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Health Science, Aomori University of Health and Welfare"},{"subitem_text_value":"Department of Hygiene and Preventive Medicine, Iwate medical University"},{"subitem_text_value":"Shokei Gakuin University"},{"subitem_text_value":"Nursing School, National Defense Medical College"},{"subitem_text_value":"Department of Plastic and Reconstructive Surgery, Hirosaki University of Graduate School of Medicine Correspondence: I. Takahashi"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ito, Haruyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takahashi, Ippei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuzaka, Masashi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Lee, Sangun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Itai, Kazuyoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukui, Shinji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hamada, Naoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Saito, Yuriko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Umeda, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakaji, Shigeyuki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_63(2-4)_85.pdf","filesize":[{"value":"780.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_63(2-4)_85.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3746/files/HirosakiMedJ_63(2-4)_85.pdf"},"version_id":"4b5ecead-90f3-42f0-a753-872745ccfe83"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"微量元素","subitem_subject_scheme":"Other"},{"subitem_subject":"セレン","subitem_subject_scheme":"Other"},{"subitem_subject":"好中球","subitem_subject_scheme":"Other"},{"subitem_subject":"活性酸素種","subitem_subject_scheme":"Other"},{"subitem_subject":"一般住民","subitem_subject_scheme":"Other"},{"subitem_subject":"trace elements","subitem_subject_scheme":"Other"},{"subitem_subject":"selenium","subitem_subject_scheme":"Other"},{"subitem_subject":"neutrophil","subitem_subject_scheme":"Other"},{"subitem_subject":"reactive oxygen species","subitem_subject_scheme":"Other"},{"subitem_subject":"general population","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Influence of Trace Elements within Normal Physiological Range on Neutrophil Basal Reactive Oxygen Species Production in the Japanese General Population","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Influence of Trace Elements within Normal Physiological Range on Neutrophil Basal Reactive Oxygen Species Production in the Japanese General Population"}]},"item_type_id":"3","owner":"3","path":["651"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-12-07"},"publish_date":"2012-12-07","publish_status":"0","recid":"3746","relation_version_is_last":true,"title":["Influence of Trace Elements within Normal Physiological Range on Neutrophil Basal Reactive Oxygen Species Production in the Japanese General Population"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:10:13.287615+00:00"}