{"created":"2023-05-15T09:02:51.924831+00:00","id":3752,"links":{},"metadata":{"_buckets":{"deposit":"73bd63fd-07fb-4d76-9b29-4b6f0d4faeb5"},"_deposit":{"created_by":3,"id":"3752","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3752"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003752","sets":["557:561:651"]},"author_link":["11488","11483","11023","11512","11508","11497","13394","11026","11492","11029","11921","13400","11502","11501","13395"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"コアグラーゼ陰性ブドウ球菌の薬剤耐性，SCCmecおよびスーパー抗原毒素遺伝子の検出と比較"}]},"item_3_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"コアグラーゼ インセイ ブドウ キュウキン ノ ヤクザイ タイセイ SCCmec オヨビ スーパー コウゲン ドクソ イデンシ ノ ケンシュツ ト ヒカク"}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-11-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-4","bibliographicPageEnd":"153","bibliographicPageStart":"143","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Coagulase-negative staphylococci （CNS） are increasingly recognized to cause clinically significant infections. To investigate relationship of antibiotic resistance profiles, staphylococcal cassette chromosome mec （SCCmec） and superantigenic toxin genes in CNS, a total of 79 clinical CNS isolates from patients with surgical operations were comprehensively determined for minimum inhibitory concentration （MIC） of antibiotics, and searched for SCCmec and staphylococcal superantigenic toxin genes by novel multiplex PCR. Among 79 CNS isolates, at least one SCCmec gene was detected in 55 isolates （69.6%）. The most of SCCmec type was type III （36.7%）, and other detected types were type IVa（ 20.3%）, type II（ 19.0%）, type V（ 16.5%）, type I（ 15.2%）, and type IVb（ 3.8%）. The isolates with type I or IVa gene showed highly resistance to clindamycin and gentamicin, the isolates with type II showed more resistance to teicoplanin, the isolates with type III or type V showed more resistance to clindamycin. se and tst-1 genes were detected in none of the CNS isolates tested. These results suggested that there is high prevalence of SCCmec in clinical CNS isolates, and the SCCmec types are related to the resistances against specific antibiotics, but SCCmec do not related to superantigenic toxin genes in the CNS.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 63, 2012, p.143-153","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11497","nameIdentifierScheme":"WEKO"}],"names":[{"name":"アベ, ユキコ"}]},{"nameIdentifiers":[{"nameIdentifier":"13394","nameIdentifierScheme":"WEKO"}],"names":[{"name":"フ, ドンリアン"}]},{"nameIdentifiers":[{"nameIdentifier":"13395","nameIdentifierScheme":"WEKO"}],"names":[{"name":"オモエ, カツヒコ"}]},{"nameIdentifiers":[{"nameIdentifier":"11026","nameIdentifierScheme":"WEKO"}],"names":[{"name":"フクダ, イクオ"}]},{"nameIdentifiers":[{"nameIdentifier":"11501","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ナカネ, アキオ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11488","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"425","nameIdentifierScheme":"研究者総覧","nameIdentifierURI":"http://hue2.jm.hirosaki-u.ac.jp/html/425_ja.html"}],"names":[{"name":"阿部, 由紀子"}]},{"nameIdentifiers":[{"nameIdentifier":"11483","nameIdentifierScheme":"WEKO"}],"names":[{"name":"胡, 東良"}]},{"nameIdentifiers":[{"nameIdentifier":"13400","nameIdentifierScheme":"WEKO"}],"names":[{"name":"重茂, 克彦"}]},{"nameIdentifiers":[{"nameIdentifier":"11023","nameIdentifierScheme":"WEKO"}],"names":[{"name":"福田, 幾夫"}]},{"nameIdentifiers":[{"nameIdentifier":"11492","nameIdentifierScheme":"WEKO"}],"names":[{"name":"中根, 明夫"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"基礎医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"弘前大学大学院保健学研究科医療生命科学領域病態解析科学"},{"subitem_text_value":"弘前大学大学院医学研究科感染生体防御学"},{"subitem_text_value":"岩手大学農学部獣医学"},{"subitem_text_value":"弘前大学大学院医学研究科胸部心臓血管外科学"},{"subitem_text_value":"Department of Pathogenic Analysis, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences"},{"subitem_text_value":"Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Veterinary Medicine, Faculty of Agriculture, Iwate University"},{"subitem_text_value":"Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Abe, Yukiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hu, Dong-Liang"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Omoe, Katsuhiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuda, Ikuo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakane, Akio"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_63(2-4)_143.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_63(2-4)_143.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3752/files/HirosakiMedJ_63(2-4)_143.pdf"},"version_id":"33e929d6-57cc-4276-8fed-0d00f7d3c89f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ブドウ球菌","subitem_subject_scheme":"Other"},{"subitem_subject":"薬剤耐性","subitem_subject_scheme":"Other"},{"subitem_subject":"SCCmec","subitem_subject_scheme":"Other"},{"subitem_subject":"マルチプレックスPCR","subitem_subject_scheme":"Other"},{"subitem_subject":"スーパー抗原","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Comparative Prevalence of Antibiotic Resistance, Staphylococcal Cassette Chromosome Mec and Superantigenic Toxin Genes in Coagulase-Negative Staphylococci","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparative Prevalence of Antibiotic Resistance, Staphylococcal Cassette Chromosome Mec and Superantigenic Toxin Genes in Coagulase-Negative Staphylococci"}]},"item_type_id":"3","owner":"3","path":["651"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-12-07"},"publish_date":"2012-12-07","publish_status":"0","recid":"3752","relation_version_is_last":true,"title":["Comparative Prevalence of Antibiotic Resistance, Staphylococcal Cassette Chromosome Mec and Superantigenic Toxin Genes in Coagulase-Negative Staphylococci"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:17:20.715476+00:00"}