{"created":"2023-05-15T09:02:53.097179+00:00","id":3770,"links":{},"metadata":{"_buckets":{"deposit":"16345e50-e586-4c1e-854d-5ee3468ffc46"},"_deposit":{"created_by":3,"id":"3770","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3770"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003770","sets":["557:561:654"]},"author_link":["13725","11519","11514","13727"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Supplement","bibliographicPageEnd":"S5","bibliographicPageStart":"S1","bibliographicVolumeNumber":"64","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"group box 1 （HMGB1）, which mobilizes a sub-population of non-hematopoietic cells from bone marrow into the circulation to repair skin and restore Col 7 expression. These bone marrow-derived epithelial stem/progenitor cells are derived from a lineage-negative, platelet-derived growth factor alpha-positive mesenchymal stem cell pool in bone marrow, which represents less than 0.3% of the total bone marrow cell population. In addition, systemic administration of HMGB1 to wounded wild-type mice leads to faster wound healing with recruitment of these bone marrow cells to the wounded skin. This study identifies a suitable cell population for cell therapy approaches in individuals with RDEB, but also has broader implications for clinical medicine in identifying a means of mobilizing and recruiting a key population of bone marrow cells germane to tissue repair.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 64(Suppl.), 2013, p.S1-S5","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"11519","nameIdentifierScheme":"WEKO"}],"names":[{"name":"タマイ, カツト"}]},{"nameIdentifiers":[{"nameIdentifier":"13727","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カネダ, ヤスフミ"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Stem Cell Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University"},{"subitem_text_value":"Gene Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tamai, Katsuto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kaneda, Yasufumi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_64_S1.pdf","filesize":[{"value":"329.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_64_S1.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3770/files/HirosakiMedJ_64_S1.pdf"},"version_id":"1c8737ec-d66f-487d-84ad-ad9081c6f497"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"mesenchymal stem cell","subitem_subject_scheme":"Other"},{"subitem_subject":"high mobility group box 1","subitem_subject_scheme":"Other"},{"subitem_subject":"epidermolysis bullosa","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo"}]},"item_type_id":"3","owner":"3","path":["654"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-04-30"},"publish_date":"2013-04-30","publish_status":"0","recid":"3770","relation_version_is_last":true,"title":["Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:33:39.332780+00:00"}