{"created":"2023-05-15T09:02:53.162195+00:00","id":3771,"links":{},"metadata":{"_buckets":{"deposit":"0767da41-e805-4897-9a69-7217bf09b347"},"_deposit":{"created_by":3,"id":"3771","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3771"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003771","sets":["557:561:654"]},"author_link":["13730","13735","13731","13738","13736","13734","13733","13728","13729","13739","13732","13737"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-04-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"Supplement","bibliographicPageEnd":"S8","bibliographicPageStart":"S6","bibliographicVolumeNumber":"64","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background\nAcute renal ischemic injury （AKI） represents a major clinical problem with renal arterial clamp at partial nephrectomy. The use of therapy using adipose tissue-derived stem cells（ASCs） has been suggested as a potential modality to attenuate the ischemic renal damage.\nMethods\nWe investigated the possible reno-protection of pretreatment of ASCs before and after in a rat ischemia–reperfusion （I–R） model of AKI. Twenty-four hours post-ischemia, blood flow in peritubular capillaries （PTC） was measured using intravital videomicroscopy.\nResults\nWe demonstrated that ADRC therapy significantly reduced serum creatinine and BUN. Histological analysis further validated a significantly attenuated tubular damage. Intravital videomicroscopy and measurement of red blood cell velocity in peritubular capillaries showed ASCs-injected kidneys displayed significant hemodynamic improvement.\nConclusions\nThe subscapular administration of ASCs to the kidney attenuates I/R renal injury though anti-inflammation, antiapotoyic effect and peritubular capillary microcirculation. The present study suggests that ASCs would be a useful tool in preventing ischemic kidney damage in the clinical setting.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 64(Suppl.), 2013, p.S6-S8","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"13734","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヤマモト, トクノリ"}]},{"nameIdentifiers":[{"nameIdentifier":"13735","nameIdentifierScheme":"WEKO"}],"names":[{"name":"フナハシ, ヤスト"}]},{"nameIdentifiers":[{"nameIdentifier":"13736","nameIdentifierScheme":"WEKO"}],"names":[{"name":"マツカワ, ヨシヒサ"}]},{"nameIdentifiers":[{"nameIdentifier":"13737","nameIdentifierScheme":"WEKO"}],"names":[{"name":"カトウ, マサシ"}]},{"nameIdentifiers":[{"nameIdentifier":"13738","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヨシノ, ヤスシ"}]},{"nameIdentifiers":[{"nameIdentifier":"13739","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ゴトウ, モモカズ"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Urology, Nagoya University"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamamoto, Tokunori"}],"nameIdentifiers":[{"nameIdentifier":"13728","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Funahashi, Yasuto"}],"nameIdentifiers":[{"nameIdentifier":"13729","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Mastukawa, Yoshihisa"}],"nameIdentifiers":[{"nameIdentifier":"13730","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kato, Masashi"}],"nameIdentifiers":[{"nameIdentifier":"13731","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yoshino, Yasushi"}],"nameIdentifiers":[{"nameIdentifier":"13732","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Gotoh, Momokzu"}],"nameIdentifiers":[{"nameIdentifier":"13733","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_64_S6.pdf","filesize":[{"value":"345.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_64_S6.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3771/files/HirosakiMedJ_64_S6.pdf"},"version_id":"41c81641-155c-4ae7-b447-f19b7def7bfa"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ADIPOSE TISSUE-DERIVED STEM CELLS","subitem_subject_scheme":"Other"},{"subitem_subject":"ISCHEMIA-REPERFUSION-INDUCED ACUTE KIDNEY INJURY","subitem_subject_scheme":"Other"},{"subitem_subject":"RENAL PROTECT","subitem_subject_scheme":"Other"},{"subitem_subject":"CYTOKINES","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Pretreatment of Renal Supscapular Administration of Adipose Tissue-derived Stem Cells Ameliorate Ischemiareperfusion-Induced Acute Kidney Injury","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Pretreatment of Renal Supscapular Administration of Adipose Tissue-derived Stem Cells Ameliorate Ischemiareperfusion-Induced Acute Kidney Injury"}]},"item_type_id":"3","owner":"3","path":["654"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-04-30"},"publish_date":"2013-04-30","publish_status":"0","recid":"3771","relation_version_is_last":true,"title":["Pretreatment of Renal Supscapular Administration of Adipose Tissue-derived Stem Cells Ameliorate Ischemiareperfusion-Induced Acute Kidney Injury"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-05-16T06:42:14.470285+00:00"}