{"created":"2023-05-15T09:02:55.109824+00:00","id":3801,"links":{},"metadata":{"_buckets":{"deposit":"ef4a3bf0-7098-4d32-ba55-142efd0d81fd"},"_deposit":{"created_by":3,"id":"3801","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3801"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003801","sets":["557:561:655"]},"author_link":["14176","14179","14167","14175","14168","14173","12308","14169","14163","14171","14174","14164","12313","14180","14170","14177","14165","12303"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"がん細胞と非がん細胞の鑑別における無染色の液状処理細胞診を用いた紫外顕微分光法の有用性"}]},"item_3_alternative_title_22":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"ガン サイボウ ト ヒガン サイボウ ノ カンベツ ニオケル ムセンショク ノ エキジョウ ショリ サイボウシン オ モチイタ シガイ ケンビ ブンコウホウ ノ ユウヨウセイ"}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-04-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"94","bibliographicPageStart":"82","bibliographicVolumeNumber":"65","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Object: To investigate the usefulness of ultraviolet-microscopic spectroscopy （UV-MS） of unstained cells by liquid-based cytology （LBC） to objectively differentiate non-cancer from cancer cells. Study Design: Cultured cells were used as the sample cells: 100 non-cancer cells and 200 cancer cells. The sample measurement region was a 166.4-μm2 area in the nuclear region of sample cells. On UV-MS, data of 260, 280, 300, 320, and 340 nm were extracted from the transmittance spectrum of 260-350-nm ultraviolet （UV） wavelengths and analyzed. Result: At a 300-nm UV wavelength, transmittances in non-cancer and cancer cells were 79.7±5.0 and 64.1±5.0%, respectively, being signifi cantly lower in cancer cells （P<0.01）. On discriminant analysis, a linear discriminant function: Z=0.61 x transmittance（ 300 nm） - 44.02, was obtained. When the function value is positive and negative, the cell is judged as a cancer or non-cancer cell, respectively. The accuracy of this linear discriminant function was 96.3%, sensitivity was 98.0%, specifi city was 93.0%. Conclusions: UV-MS on unstained cells by LBC yields an objective value to discriminate non-cancer from cancer cells. Since LBC is a sample processing procedure which will be increasingly used in the future, we are planning to further investigate its applicability to clinical specimens based on this study.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 65, 2014, p.82-94","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"14169","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヨシオカ, ハルヒコ"}]},{"nameIdentifiers":[{"nameIdentifier":"14170","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ホシアイ, ケイタ"}]},{"nameIdentifiers":[{"nameIdentifier":"14171","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ナカムラ, トシヤ"}]},{"nameIdentifiers":[{"nameIdentifier":"12308","nameIdentifierScheme":"WEKO"}],"names":[{"name":"サトウ, タツスケ"}]},{"nameIdentifiers":[{"nameIdentifier":"14173","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ワシヤ, キヨタダ"}]},{"nameIdentifiers":[{"nameIdentifier":"14174","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ワタナベ, ジュン"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"14175","nameIdentifierScheme":"WEKO"}],"names":[{"name":"吉岡, 治彦"}]},{"nameIdentifiers":[{"nameIdentifier":"14176","nameIdentifierScheme":"WEKO"}],"names":[{"name":"星合, 桂太"}]},{"nameIdentifiers":[{"nameIdentifier":"14177","nameIdentifierScheme":"WEKO"}],"names":[{"name":"中村, 敏也"}]},{"nameIdentifiers":[{"nameIdentifier":"12313","nameIdentifierScheme":"WEKO"}],"names":[{"name":"佐藤, 達資"}]},{"nameIdentifiers":[{"nameIdentifier":"14179","nameIdentifierScheme":"WEKO"}],"names":[{"name":"鷲谷, 清忠"}]},{"nameIdentifiers":[{"nameIdentifier":"14180","nameIdentifierScheme":"WEKO"}],"names":[{"name":"渡邉, 純"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"491.65","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"基礎医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Pathologic Analysis, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences"},{"subitem_text_value":"Department of Pathologic Analysis, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences"},{"subitem_text_value":"Department of Biomedical Sciences, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences"},{"subitem_text_value":"CLARO, Inc."},{"subitem_text_value":"Department of Pathologic Analysis, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences"},{"subitem_text_value":"Department of Pathologic Analysis, Division of Medical Life Sciences, Hirosaki University Graduate School of Health Sciences"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yoshioka, Haruhiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hoshiai, Keita"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Toshiya"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Sato, Tatsusuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Washiya, Kiyotada"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Jun"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_65(1)_82.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_65(1)_82.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3801/files/HirosakiMedJ_65(1)_82.pdf"},"version_id":"9141c91d-1199-4a9b-80b1-c416e156ccb2"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Ultraviolet-microscopic spectroscopy","subitem_subject_scheme":"Other"},{"subitem_subject":"Liquid-based cytology","subitem_subject_scheme":"Other"},{"subitem_subject":"Discriminant analysis","subitem_subject_scheme":"Other"},{"subitem_subject":"Unstained cells","subitem_subject_scheme":"Other"},{"subitem_subject":"紫外顕微分光法","subitem_subject_scheme":"Other"},{"subitem_subject":"液状処理細胞診","subitem_subject_scheme":"Other"},{"subitem_subject":"判別分析","subitem_subject_scheme":"Other"},{"subitem_subject":"無染色細胞","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Usefulness of Ultraviolet-Microscopic Spectroscopy on Unstained Cells by Liquid-Based Cytology for Objective Differentiation between Non-Cancer from Cancer Cells","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Usefulness of Ultraviolet-Microscopic Spectroscopy on Unstained Cells by Liquid-Based Cytology for Objective Differentiation between Non-Cancer from Cancer Cells"}]},"item_type_id":"3","owner":"3","path":["655"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-05-22"},"publish_date":"2014-05-22","publish_status":"0","recid":"3801","relation_version_is_last":true,"title":["Usefulness of Ultraviolet-Microscopic Spectroscopy on Unstained Cells by Liquid-Based Cytology for Objective Differentiation between Non-Cancer from Cancer Cells"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:02:42.994538+00:00"}