@article{oai:hirosaki.repo.nii.ac.jp:00003841,
 author = {Sakuraba, Shingo and Morohashi, Satoko and Yoshizawa, Tadashi and Tsutsumi, shinji and Kimura, Norihisa and Kudo, Daisuke and Ishido, Keinosuke and Toyoki, Yoshikazu and Hakamada, Kenichi and Kijima, Hiroshi},
 issue = {1},
 journal = {弘前医学},
 month = {Apr},
 note = {Both pancreas head ductal carcinoma（ PHDC） and distal bile duct carcinoma（ DBDC） are located within the pancreas head/intra-pancreatic bile duct region, and are the most aggressive malignancies with poor patient prognosis. In the present study, we demonstrated clinicopathological features and patients prognosis of PHDC/DBDC. We examined total 87 surgically resected cases of PHDC （40 cases） and DBDC （47 cases）. PHDC showed frequent neural invasion （85.0%） and lymph node metastasis （77.5%）, compared with DBDC （57.4% and 40.4% respectively）, resulting in the poorer prognosis（ P=0.0219） than DBDC. In addition, PHDC expressed MUC2（ 10.0%）and MUC6 （25.0%） less frequently, compared with DBDC （36.2% and 55.3%, respectively）. MUC5AC-negative PHDC exhibited significantly poorer patient’s prognosis, compared with MUC5AC-positive PHDC （P=0.0111）, MUC5ACpositive DBDC （P=0.000162）, and MUC5AC-negative DBDC （P=0.00416）. In conclusion, MUC5AC-negative PHDC showed significantly poor patient’s prognosis., 弘前医学. 66, 2015, p.28-37},
 pages = {28--37},
 title = {MUC5AC-Negative Phenotype is Correlated with Poor Patient Prognosis of Pancreas Head Ductal Carcinoma.},
 volume = {66},
 year = {2015}
}