{"created":"2023-05-15T09:02:57.529314+00:00","id":3841,"links":{},"metadata":{"_buckets":{"deposit":"69a2d30b-e29a-4622-b282-86741116e620"},"_deposit":{"created_by":3,"id":"3841","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3841"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003841","sets":["557:561:657"]},"author_link":["11769","11302","13869","13407","13337","13001","12410","14410","15803","13888"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-04-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"37","bibliographicPageStart":"28","bibliographicVolumeNumber":"66","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Both pancreas head ductal carcinoma（ PHDC） and distal bile duct carcinoma（ DBDC） are located within the pancreas head/intra-pancreatic bile duct region, and are the most aggressive malignancies with poor patient prognosis. In the present study, we demonstrated clinicopathological features and patients prognosis of PHDC/DBDC. We examined total 87 surgically resected cases of PHDC （40 cases） and DBDC （47 cases）. PHDC showed frequent neural invasion （85.0%） and lymph node metastasis （77.5%）, compared with DBDC （57.4% and 40.4% respectively）, resulting in the poorer prognosis（ P=0.0219） than DBDC. In addition, PHDC expressed MUC2（ 10.0%）and MUC6 （25.0%） less frequently, compared with DBDC （36.2% and 55.3%, respectively）. MUC5AC-negative PHDC exhibited significantly poorer patient’s prognosis, compared with MUC5AC-positive PHDC （P=0.0111）, MUC5ACpositive DBDC （P=0.000162）, and MUC5AC-negative DBDC （P=0.00416）. In conclusion, MUC5AC-negative PHDC showed significantly poor patient’s prognosis.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 66, 2015, p.28-37","subitem_description_type":"Other"}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sakuraba, Shingo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morohashi, Satoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshizawa, Tadashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsutsumi, shinji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kimura, Norihisa"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kudo, Daisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishido, Keinosuke"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Toyoki, Yoshikazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hakamada, Kenichi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kijima, Hiroshi"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_66(1)_28.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_66(1)_28.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3841/files/HirosakiMedJ_66(1)_28.pdf"},"version_id":"019a2e7c-2aae-44be-b2e5-cd08949820fe"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"mucin","subitem_subject_scheme":"Other"},{"subitem_subject":"MUC5AC","subitem_subject_scheme":"Other"},{"subitem_subject":"pancreas cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"bile duct cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"patient prognosis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"MUC5AC-Negative Phenotype is Correlated with Poor Patient Prognosis of Pancreas Head Ductal Carcinoma.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"MUC5AC-Negative Phenotype is Correlated with Poor Patient Prognosis of Pancreas Head Ductal Carcinoma."}]},"item_type_id":"3","owner":"3","path":["657"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-05-25"},"publish_date":"2015-05-25","publish_status":"0","recid":"3841","relation_version_is_last":true,"title":["MUC5AC-Negative Phenotype is Correlated with Poor Patient Prognosis of Pancreas Head Ductal Carcinoma."],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:10:01.931532+00:00"}