@article{oai:hirosaki.repo.nii.ac.jp:00003885,
 author = {Morohashi, Satoko and Morohashi, Hajime and Yoshizawa, Tadashi and Tanaka, Masanori and Mikami, Tatsuya and Kagiya, Takuji and Saito, Takeshi and Hirai, Hideaki and Haga, Toshihiro and Wu, Yunyan and Hakamada, Kenichi and Kijima, Hiroshi},
 issue = {1},
 journal = {弘前医学},
 month = {Jul},
 note = {There are no reports on the degree of inflammation in the residual rectal mucosa in
asymptomatic UC patients after an operation for ileal pouch anal canal anastomosis（ IACA）.
Methods: We studied the residual rectal mucosal biopsies and rectal mucosa from the surgical specimens of 12
asymptomatic postoperative UC cases. We analyzed the degree of inflammation, including crypt architecture and
mucus content in the rectal mucosa.
Results: Two pathological active cases （16.7%）, four resolving cases （33.3%）, and six remission cases （50%） were
observed in the residual rectal mucosa. In terms of the degree of pathological inflammation in the residual rectal
mucosa, one case （1/12, 8.3%） was upregulated, seven cases （7/12, 58.3%） were stable, and four cases （4/12, 33.3%）
were downregulated compared with the rectal mucosa of the surgical specimens.
Conclusions: We determined the natural history of the degree of inflammation on the residual rectal mucosa in
postoperative UC patients. Eight cases （8/12, 66.6%） of asymptomatic UC patients were associated with prolonged
inflammation after an IACA operation in the residual rectal mucosa compared with that in the rectal mucosa of the
surgical specimens. Therefore, we could identify patients with prolonged inflammation in asymptomatic UC cases by a residual rectal mucosal biopsy., 弘前医学. 67, 2016, p.92-101},
 pages = {92--101},
 title = {Morphological Analysis of the Residual Rectal Mucosa in 12 Postoperative Ulcerative Colitis Patients},
 volume = {67},
 year = {2016}
}