{"created":"2023-05-15T09:03:00.915464+00:00","id":3902,"links":{},"metadata":{"_buckets":{"deposit":"1fcd9a8c-a523-4022-98b6-b061ac8c2c83"},"_deposit":{"created_by":3,"id":"3902","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3902"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00003902","sets":["557:561:660"]},"author_link":["14831","14789","14792","14790","14828","14702","14440","14830","11458","11980","14438","11861"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-02-27","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2-4","bibliographicPageEnd":"157","bibliographicPageStart":"153","bibliographicVolumeNumber":"67","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We examined the effects of enflurane anesthesia on the mouse cardiac autonomic nervous system using\nelectrocardiogram（ ECG） analysis. Enflurane had a lower effect on heart rate（ HR） compared to isoflurane, which is\nmore widely used in small animal studies. Under anesthesia with 3 or 4% of enflurane, administration of propranolol\nhad a significant effect on HR. Enflurane increased R-R interval length in a dose-dependent fashion, and the R-R\ninterval became unstable at high concentrations. Although HR decreased with high doses of enflurane, we observed\nnormal sinus rhythm and no arrhythmia. These results suggest that the effect of enflurane anesthesia is acceptable\neven though the drug can lead to cardiac instability. No remarkable changes were observed in HR frequency. These results suggest that enflurane anesthesia may be suitable for cardiac autonomic nervous system analysis.","subitem_description_type":"Abstract"}]},"item_3_description_7":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"弘前医学. 67, 2017, p.153-157","subitem_description_type":"Other"}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_3_subject_23":{"attribute_name":"NIIサブジェクト","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_scheme":"Other"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Pharmacology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Anesthesiology, Hirosaki UniversityGraduate School of Medicine"},{"subitem_text_value":"Department of Anesthesiology, Hirosaki UniversityGraduate School of Medicine"},{"subitem_text_value":"Department of Vascular Biology, Institute of Brain Science, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Anesthesiology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Pharmacology, Hirosaki University Graduate School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ogata, Yoshiki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yonekura, Manabu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaki, Rouichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Han, Chong"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujiwara, Tomonori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Seya, Kazuhiko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Niwa, Hidetoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kushikata, Tetsuya"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Imaizumi, Tadaatsu"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Hirota, Kazuyoshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Tomita, Hirofumi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Murakami, Manabu"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-03-13"}],"displaytype":"detail","filename":"HirosakiMedJ_67(2-4)_153.pdf","filesize":[{"value":"259.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_67(2-4)_153.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/3902/files/HirosakiMedJ_67(2-4)_153.pdf"},"version_id":"440224f4-42c3-4b24-87c2-2504bee97fcb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Autonomic nervous system","subitem_subject_scheme":"Other"},{"subitem_subject":"enflurane","subitem_subject_scheme":"Other"},{"subitem_subject":"halothane","subitem_subject_scheme":"Other"},{"subitem_subject":"inhalation anesthesia","subitem_subject_scheme":"Other"},{"subitem_subject":"mice","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of Enflurane on Cardiac Autonomic Nervous Activity in Mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of Enflurane on Cardiac Autonomic Nervous Activity in Mice"}]},"item_type_id":"3","owner":"3","path":["660"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-03-09"},"publish_date":"2017-03-09","publish_status":"0","recid":"3902","relation_version_is_last":true,"title":["Effects of Enflurane on Cardiac Autonomic Nervous Activity in Mice"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-05-15T10:20:25.298646+00:00"}