{"created":"2023-05-15T09:04:24.090062+00:00","id":5477,"links":{},"metadata":{"_buckets":{"deposit":"b7b38eb8-5c4b-4e1a-92d1-c39af66c31f1"},"_deposit":{"created_by":11,"id":"5477","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"5477"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00005477","sets":["953:954:955"]},"author_link":["13944","19763","13943","16061","15954","16067","13951","16200","13980","16064","11600","11606","19762","16194","11610","11604","15942","16197","11890"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-09-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"39","bibliographicPageEnd":"64505","bibliographicPageStart":"65492","bibliographicVolumeNumber":"8","bibliographic_titles":[{"bibliographic_title":"ONCOTARGET"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: The recurrence risk stratification and the cost effectiveness of oncological surveillance after radical cystectomy are not clear. We aimed to develop a risk stratification and a surveillance protocol with improved cost effectiveness after radical cystectomy. \n\nResults: Of 581 enrolled patients, 175 experienced disease recurrences. The pathology-based protocol presented significant differences in recurrence-free survival between normal-and high-risk patients, but the medical expense was high, especially in normal-risk (<= pT2pN0) patients. Cox regression analysis identified six factors associated with recurrence-free survival. Risk score-based 5-year follow-up was significantly more cost effective than the pathology-based protocol. \n\nMaterials and Methods: We retrospectively evaluated 581 patients with radical cystectomy for muscle-invasive bladder cancer at 4 hospitals. Patients with routine oncological follow-up were stratified into normal-and high-risk groups by a pathology-based protocol utilizing pT, pN, lymphovascular invasion, and histology. Cost effectiveness of the pathology-based protocol was evaluated and a risk-score-based protocol was developed to optimize cost effectiveness. Risk-scores were calculated by summing risk factors independently associated with recurrence-free survival. Patients were stratified by low-, intermediate-, and high-risk score. Estimated cost per one recurrence detection by the pathology and by risk-scores were compared. \n\nConclusions: Risk-score-stratified surveillance protocol has potential to reduce over-evaluation after radical cystectomy without adverse effects on medical cost.","subitem_description_type":"Abstract"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_relation_13":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.18632/oncotarget.19043","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1949-2553","subitem_source_identifier_type":"ISSN"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Adv Transplant & Regenerat Med, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Adv Transplant & Regenerat Med, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Aomori Rosai Hosp, Dept Urol"},{"subitem_text_value":"Mutsu Gen Hosp, Dept Urol"},{"subitem_text_value":"Aomori Prefectural Cent Hosp, Dept Urol"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kusaka, Ayumu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hatakeyama, Shingo"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Hosogoe, Shogo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hamano, Itsuto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iwamura, Hiromichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujita, Naoki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukushi, Ken"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Narita, Takuma"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hagiwara, kazuhisa"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Hayato"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Tobisawa, Yuki"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Yoneyama, Tohru"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Yoneyama, Takahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hashimoto, Yasuhiro"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Koie, Takuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshikawa, Kazuaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawaguchi, Toshiaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohyama, Chikara"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-03-08"}],"displaytype":"detail","filename":"oncotarget-65492.pdf","filesize":[{"value":"5.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"oncotarget-65492","url":"https://hirosaki.repo.nii.ac.jp/record/5477/files/oncotarget-65492.pdf"},"version_id":"a06af066-6060-427e-bfd6-e7eca9dfbbdd"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Risk-stratified surveillance and cost effectiveness of follow-up after radical cystectomy in patients with muscle-invasive bladder cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Risk-stratified surveillance and cost effectiveness of follow-up after radical cystectomy in patients with muscle-invasive bladder cancer"}]},"item_type_id":"3","owner":"11","path":["955"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-03-08"},"publish_date":"2019-03-08","publish_status":"0","recid":"5477","relation_version_is_last":true,"title":["Risk-stratified surveillance and cost effectiveness of follow-up after radical cystectomy in patients with muscle-invasive bladder cancer"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T10:00:30.235907+00:00"}