{"created":"2023-05-15T09:04:24.154808+00:00","id":5478,"links":{},"metadata":{"_buckets":{"deposit":"9b79bfe7-ae92-4cc4-aaf3-210757a1152e"},"_deposit":{"created_by":11,"id":"5478","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"5478"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00005478","sets":["953:954:955"]},"author_link":["13944","19763","15954","11600","19765","19772","11890","19768","16194","19766","13943","16061","13980","11606","19762","19774","11604","15942","19771","16067","13951","19770","19775","11610","19773","19769","19767"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-10-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"47","bibliographicPageEnd":"83194","bibliographicPageStart":"83183","bibliographicVolumeNumber":"8","bibliographic_titles":[{"bibliographic_title":"ONCOTARGET"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: To evaluate the impact of preoperative chronic kidney disease (CKD) on oncological outcomes in patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy. \n\nMethods: A total of 426 patients who underwent radical nephroureterectomy at five medical centers between February 1995 and February 2017 were retrospectively examined. Oncological outcomes, including intravesical recurrence-free, visceral recurrence-free, cancer-specific, and overall survival rates (intravesical RFS, visceral RFS, CSS, and OS, respectively) stratified by preoperative CKD status (CKD vs. non-CKD) were investigated. Cox proportional hazards regression analysis was performed using inverse probability of treatment weighting (IPTW) to evaluate the impact of preoperative CKD on prognosis and a prognostic factor-based risk stratification nomogram was developed. \n\nResults: Of the 426 patients, 250 (59%) were diagnosed with CKD before radical nephroureterectomy. Before the background adjustment, intravesical RFS, visceral RFS, CSS, and OS after radical nephroureterectomy were significantly shorter in the CKD group than in the non-CKD group. Background-adjusted IPTW analysis demonstrated that preoperative CKD was significantly associated with poor visceral RFS, CSS, and OS after radical nephroureterectomy. Intravesical RFS was not significantly associated with preoperative CKD. The nomogram for predicting 5-year visceral RFS and CSS probability demonstrated a significant correlation with actual visceral RFS and CSS (c-index = 0.85 and 0.83, respectively). \n\nConclusions: Upper tract urothelial carcinoma patients with preoperative CKD had a significantly lower survival probability than those without CKD.","subitem_description_type":"Abstract"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_relation_13":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.18632/oncotarget.20554","subitem_relation_type_select":"DOI"}}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1949-2553","subitem_source_identifier_type":"ISSN"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Adv Transplant & Regenerat Med, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Adv Transplant & Regenerat Med, Grad Sch Med"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"},{"subitem_text_value":"Aomori Rosai Hosp, Dept Urol"},{"subitem_text_value":"Mutsu Gen Hosp, Dept Urol"},{"subitem_text_value":"Tsugaru Gen Hosp, Dept Urol"},{"subitem_text_value":"Aomori Prefectural Cent Hosp, Dept Urol"},{"subitem_text_value":"Tohoku Med & Pharmaceut Univ, Dept Urol"},{"subitem_text_value":"Hirosaki Univ, Dept Urol, Grad Sch Med"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kodama, Hirotake"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hatakeyama, Shingo"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Fujita, Naoki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iwamura, Hiromichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Anan, Go"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukushi, Ken"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Narita, Takuma"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanaka, Toshikazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kubota, Yuka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Horiguchi, Hirotaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Momota, Masaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kido, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsumoto, Teppei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Soma, Osamu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hamano, Itsuto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Hayato"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Tobisawa, Yuki"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Yoneyama, Tohru"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Yoneyama, Takahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hashimoto, Yasuhiro"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Koie, Takuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshikawa, Kazuaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sasaki, Atsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawaguchi, Toshiaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Makoto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohyama, Chikara"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-03-08"}],"displaytype":"detail","filename":"oncotarget-83183.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"oncotarget-83183","url":"https://hirosaki.repo.nii.ac.jp/record/5478/files/oncotarget-83183.pdf"},"version_id":"6b127741-a586-4ccb-9da1-198acc78790c"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Preoperative chronic kidney disease predicts poor oncological outcomes after radical nephroureterectomy in patients with upper urinary tract urothelial carcinoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Preoperative chronic kidney disease predicts poor oncological outcomes after radical nephroureterectomy in patients with upper urinary tract urothelial carcinoma"}]},"item_type_id":"3","owner":"11","path":["955"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-03-08"},"publish_date":"2019-03-08","publish_status":"0","recid":"5478","relation_version_is_last":true,"title":["Preoperative chronic kidney disease predicts poor oncological outcomes after radical nephroureterectomy in patients with upper urinary tract urothelial carcinoma"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T10:00:31.009376+00:00"}