{"created":"2023-05-15T09:04:26.683473+00:00","id":5517,"links":{},"metadata":{"_buckets":{"deposit":"1d1a61cc-d480-4b87-8338-bea6ecb7e2a0"},"_deposit":{"created_by":11,"id":"5517","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"5517"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00005517","sets":["557:561:958"]},"author_link":["12240","14671","13600","11855","13668","12239"],"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-03-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"118","bibliographicPageStart":"108","bibliographicVolumeNumber":"69","bibliographic_titles":[{"bibliographic_title":"弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It has been reported that an association between gut microbiota and obesity, and changes in the composition of gut microbiota have been reported with aging. The aim of this study is clarify the relationship between obesity and gut microbiota as a function of age. Furthermore, the impact of lifestyle factors（ alcoholic drink and smoking） on gut microbiota were discussed. Fecal samples from 1082 healthy Japanese adults aged 19–90 years who participated in the Iwaki Health Promotion Project in 2014 were analyzed by using 16S rDNA gene-targeted sequencing. The participants were stratified into six age groups: ≤39, 40–49, 50–59, 60–69, 70–79 and ≥80. The participants with a body mass index （BMI） of <25 kg/m2 were classified as non-obese, and those with a BMI of ≥25 kg/m2 were classified as obese. Changes in the composition of gut microbiota with age were different between the obese and non-obese groups.Bacterial diversity decreased with age at the phylum level, however, this diversity was not observed at the class level. The abundances of certain gut microbiota, such as Bacteroidetes and Firmicutes, were different between the obese and non-obese groups. There were no significant differences in alcoholic and smoking habits. Bacterial diversity was different with age between the obese and non-obese group. The composition of Bacteroidetes and Firmicutes changed with increasing age in the obese group.","subitem_description_type":"Abstract"}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科・弘前医学会"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_subject_19":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_3_text_4":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Medical Informatics, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Medical Informatics, Hirosaki University Hospital"},{"subitem_text_value":"Department of Faculty of Education, Hirosaki University"},{"subitem_text_value":"Department of Social Medicine, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Social Medicine, Hirosaki University Graduate School of Medicine"},{"subitem_text_value":"Department of Medical Informatics, Hirosaki University Graduate School of Medicine"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tanaka, Rina"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuzaka, Masashi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Takahashi, Ippei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sawada, Kaori"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Nakaji, Shigeyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sasaki, Yoshihiro"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-10"}],"displaytype":"detail","filename":"HirosakiMedJ_69(1-4)_108.pdf","filesize":[{"value":"541.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_69(1-4)_108.pdf","url":"https://hirosaki.repo.nii.ac.jp/record/5517/files/HirosakiMedJ_69(1-4)_108.pdf"},"version_id":"1d63b714-939a-4600-9c8c-1fad37edbe76"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"aging","subitem_subject_scheme":"Other"},{"subitem_subject":"general population","subitem_subject_scheme":"Other"},{"subitem_subject":"gut microbiota","subitem_subject_scheme":"Other"},{"subitem_subject":"lifestyle","subitem_subject_scheme":"Other"},{"subitem_subject":"obesity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Changes in Gut Microbiota Composition with Aging in Obese Adults","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Changes in Gut Microbiota Composition with Aging in Obese Adults"}]},"item_type_id":"3","owner":"11","path":["958"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-04-10"},"publish_date":"2019-04-10","publish_status":"0","recid":"5517","relation_version_is_last":true,"title":["Changes in Gut Microbiota Composition with Aging in Obese Adults"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T11:46:34.039737+00:00"}