{"created":"2023-05-15T09:04:56.795683+00:00","id":6135,"links":{},"metadata":{"_buckets":{"deposit":"ecb205e4-b5e2-4f85-830b-1b9a31370e25"},"_deposit":{"created_by":11,"id":"6135","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"6135"},"status":"published"},"_oai":{"id":"oai:hirosaki.repo.nii.ac.jp:00006135","sets":["557:561:1005"]},"author_link":["20927","12391","12397","20924","20830","20925","20831","20832","12400"],"item_3_alternative_title_21":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"A mass spectrometric analysis of a polyphenol “phlorizin” contained in the peel of the Fuji grown with a natural cultivation method that employs neither fertilizers nor pesticides and a method with no chemical fertilizers and reduced pesticide use."}]},"item_3_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-10-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"45","bibliographicPageStart":"31","bibliographicVolumeNumber":"70","bibliographic_titles":[{"bibliographic_title":"\t弘前医学"}]}]},"item_3_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"　フロリジンはりんごの果皮に高濃度に含まれるポリフェノールで，抗癌作用や血糖低下作用を示す．実際，最新の高血糖治療薬として臨床で用いられている薬剤は，フロリジンの腎特異性を高めた誘導体である．しかし，りんごを果皮ごと食用とする場合，農薬が懸念される．確かにりんご栽培には農薬の使用が不可避とされているが，青森県津軽地方には，無肥料・無農薬によるりんごの自然栽培に成功した圃場がある．そこで今回，この圃場の「ふじ」を5ヶ月間採取し，果皮のフロリジン含量を質量分析により解析した．対照には化学肥料不使用・減農薬栽培の「ふじ」を用いた．その結果，前者のフロリジン含量は後者に比べ，採取時期を問わず有意に大きいことが判明した．自然栽培されたりんごは，果実のみならず果皮のポリフェノールも安心して摂取できることから，今後の発展が期待される.\n Phlorizin, one of the major apple polyphenols that are highly contained in the peel, shows anticancer effect and lowers the blood sugar level. Indeed, a renal targeted derivative of phlorizin is the latest anti-yperglycemic drug in clinical settings. However, pesticides used may cause harm when whole apple fruits were consumed. While it was the commonly held belief that apples can't be grown without pesticides, there is an orchard cultivating apples with no pesticides nor fertilizers in Tsugaru district in Japan. Here we compared Phlorizin content by mass spectrometry in the peel of Fuji apples for five months between those grown with a natural cultivation method that employs neither fertilizers nor pesticides, and a method with no chemical fertilizers and reduced pesticide use. Results showed that the phlorizin content of the fruits grown with the former method was significantly larger than that with the latter one for all periods tested. The natural cultivation is a promising method that assures safe intake of polyphenols in not only flesh but also peels.","subitem_description_type":"Abstract"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"20831","nameIdentifierScheme":"WEKO"}],"names":[{"name":"オノ, コウキ"}]},{"nameIdentifiers":[{"nameIdentifier":"20925","nameIdentifierScheme":"WEKO"}],"names":[{"name":"イマイ, マチコ"}]},{"nameIdentifiers":[{"nameIdentifier":"12397","nameIdentifierScheme":"WEKO"}],"names":[{"name":"ヤマダ, カツヤ"}]}]},"item_3_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"20832","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ono, Koki"}]},{"nameIdentifiers":[{"nameIdentifier":"20927","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Imai, Machiko"}]},{"nameIdentifiers":[{"nameIdentifier":"12391","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yamada, Katsuya"}]}]},"item_3_publisher_35":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"弘前大学大学院医学研究科"}]},"item_3_radio_42":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_radio_item":"Article"}]},"item_3_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00211444","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0439-1721","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小野, 幸輝"}],"nameIdentifiers":[{"nameIdentifier":"20830","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"今井, 麻智子"}],"nameIdentifiers":[{"nameIdentifier":"20924","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"山田, 勝也"}],"nameIdentifiers":[{"nameIdentifier":"12400","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-11-12"}],"displaytype":"detail","filename":"HirosakiMedJ_71(1)_31.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HirosakiMedJ_71(1)_31","url":"https://hirosaki.repo.nii.ac.jp/record/6135/files/HirosakiMedJ_71(1)_31.pdf"},"version_id":"391802e5-c2e0-4d59-bd58-4d1a9bcc4680"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"自然栽培","subitem_subject_scheme":"Other"},{"subitem_subject":"りんご","subitem_subject_scheme":"Other"},{"subitem_subject":"フロリジン","subitem_subject_scheme":"Other"},{"subitem_subject":"フロレチン","subitem_subject_scheme":"Other"},{"subitem_subject":"質量分析","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"無肥料・無農薬による自然栽培法，および無化学肥料・減農薬による栽培法で生育させた「ふじ」の果皮に含まれるポリフェノール“フロリジン” の質量分析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"無肥料・無農薬による自然栽培法，および無化学肥料・減農薬による栽培法で生育させた「ふじ」の果皮に含まれるポリフェノール“フロリジン” の質量分析"}]},"item_type_id":"3","owner":"11","path":["1005"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-11-12"},"publish_date":"2020-11-12","publish_status":"0","recid":"6135","relation_version_is_last":true,"title":["無肥料・無農薬による自然栽培法，および無化学肥料・減農薬による栽培法で生育させた「ふじ」の果皮に含まれるポリフェノール“フロリジン” の質量分析"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-05-15T10:00:57.480590+00:00"}