@article{oai:hirosaki.repo.nii.ac.jp:00006739, author = {Tsuchiya, Junichiro and Saito, Norihiro and Itoga, Masamichi and Tasaka, Sadatomo and Kayaba, Hiroyuki}, issue = {1-4}, journal = {弘前医学}, month = {Mar}, note = {Background & Aims: The aim of the present study was to elucidate the possible factors responsible for thedifference in the COVID-19 case fatality rate by country. Methods: In reference to the reported studies, 14 factors possibly related to COVID-19 case fatality rate wereidentified. Of the 191 countries and regions listed on the global map of the COVID-19 dashboard by the Centerfor Systems Science and Engineering at Johns Hopkins University, 79 countries were selected taking into accountthe amount of data and its reliability. Correlations of the COVID-19 case fatality rate with 13 possible factors wereinvestigated. Epidemiological data such as food consumption, and meteorological data were obtained from publiconline databases. Results: Only fish and seafood consumption had a negative correlation with the case fatality rate by country.Seafood consumption decades ago correlated better than that in 2017. The correlation coefficient between sea foodconsumption and the COVID-19 case fatality rate decreased from -0.51 in 1970 to -0.29 in 2017. Conclusion: Fish and seafood eating habit during childhood and young adulthood may be associated with decreaseddeath by COVID-19 in their later years.}, pages = {34--42}, title = {Epidemiological investigation of the factors affecting the COVID-19 case fatality rate}, volume = {72}, year = {2022} }