| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-04-29 |
| タイトル |
|
|
タイトル |
Impact of factor Xa inhibitors on outcomes of atrial tachyarrhythmia recurrence following catheter ablation for atrial fibrillation: comparison with warfarin |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Atrial fibrillation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Catheter ablation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Factor Xa inhibitors |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Warfarin |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Fibrosis |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Washima, Shota
Hamaura, Shogo
Toyama, Yuichi
Nishizaki, Kimitaka
Kinjo, Takahiko
Ishida, Yuji
Itoh, Taihei
Kimura, Masaomi
Sasaki, Shingo
Saito, Kazumasa
Soma, Takanobu
Tomita, Hirofumi
|
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiac Remote Management System, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Advanced Management of Cardiac Arrhythmia, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Advanced Management of Cardiac Arrhythmia, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
言語 |
en |
|
値 |
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine、 Department of Cardiac Remote Management System, Hirosaki University Graduate School of Medicine、 Department of Advanced Management of Cardiac Arrhythmia, Hirosaki University Graduate School of Medicine、 Department of Advanced Therapeutics for Cardiovascular Diseases, Hirosaki University Graduate School of Medicine |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background: Factor Xa inhibitors （FXaIs） have been reported to exhibit antifibrotic effects. However, their impact on the outcomes of atrial fibrillation（ AF） ablation remains unknown. This study aimed to investigate the association between freedom from atrial tachyarrhythmia recurrence and oral anticoagulant （OAC） therapy following AF ablation.
Methods: This single-center retrospective study comprised consecutive 1,702 patients who underwent AF catheter ablation in our hospital between January 2014 and September 2021. Arrhythmia recurrence was defined as documented atrial tachyarrhythmias lasting for >30 s after the 3-month blanking period, and the recurrence rate within 12 months following ablation was compared between patients who were administered FXaIs and warfarin（ WF）.
Results: Overall, 1,321 patients（ 916 men; mean age, 64±10 years; 947 paroxysmal and 374 persistent） who continued OAC therapy following ablation were finally followed up for 12 months. Of them, 1,222 （93%） and 99 （7%） patients were administered FXaIs and WF, respectively. During the follow-up period of 324±80 days, 115 recurrences in FXaI （33, 48, and 34 in rivaroxaban, edoxaban, and apixaban, respectively） and 13 in WF were noted. The 12-month freedom from recurrence in FXaI and WF groups was 90.0% and 85.6%, respectively, with no significant difference （P=0.21）. In multivariate analysis, FXaI treatment was not an independent factor that predicts atrial tachyarrhythmia recurrence compared with WF treatment（ hazard ratio, 0.66; 95% confidence interval, 0.37–1.20; P=0.17）.
Conclusions: Regarding atrial tachyarrhythmia recurrence following AF ablation for 12 months, no significant difference was observed between FXaIs and WF treatment as post-ablation OAC therapy. |
|
言語 |
en |
| 書誌情報 |
ja : 弘前医学
en : Hirosaki Medical Journal
巻 74,
号 1-4,
p. 87-98,
発行日 2024-03-28
|
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2434-4656 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN00211444 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
弘前大学大学院医学研究科 |
|
言語 |
ja |
| 資源タイプ |
|
|
言語 |
en |
|
値 |
Article |
Hirosaki Med J 74-1-4_87.pdf (654 KB)
