| Item type |
リポジトリ登録用アイテムタイプ（シンプル）(1) |
| 公開日 |
2025-03-24 |
| タイトル |
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|
タイトル |
Assessment time of treatment response by PET-CT after superselective intra-arterial chemoradiotherapy for oral cancer |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Oral cancer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Superselective intra-arterial chemoradiotherapy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
fluorodeoxyglucose–positron emission tomography–computed tomography |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Treatment response |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Salvage operation |
| 資源タイプ |
|
|
資源タイプ識別子（シンプル） |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ（シンプル） |
journal article |
| アクセス権 |
|
|
アクセス権 |
metadata only access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_14cb |
| 著者 |
Haruka, Fukuta
Wataru, Kobayashi
Kosei, Kubota
Natsumi, Akiyama
Hiroshi, Nakagawa
Ryohei, Ito
Norihiko, Narita
Hao, Chih Chuang
Beng, Gwan Teh
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Objective: Superselective intra-arterial chemoradiotherapy (SSIACRT) is an effective treatment for advanced oral cancer. However, in cases in which treatment is ineffective and the tumor remains, salvage operation is necessary; therefore, assessment of the treatment response is extremely important. With the use of fluorodeoxyglucose–positron emission tomography (FDG-PET)–computed tomography (CT) in addition to CT and magnetic resonance imaging, the accuracy improves for the assessment of treatment response. The study aimed to clarify factors that affect the accuracy rate of FDG-PET and FDG-PET scan time, considering the possibility of a salvage operation if the tumor remains.
Methods: From April 2006 to March 2017, 69 patients (52 men and 17 women) who underwent SSIACRT and received PET were evaluated.
Results: The average FDG-PET scan time for evaluating the treatment effect was 74.1 days (range, 48–126 days) after SSIACRT, and the rate of correct diagnosis was 75.4 %. All misdiagnoses were false positives. Multivariate analysis revealed that the correct diagnosis rate depended on the severity of oral mucositis (p = 0.025; odds ratio, 1.037). In 10 cases with residual tumor and five of six cases in whom size could be measured, no regrowth was observed in 3 months. Receiver operating characteristic curve analysis indicated that the time to obtain the correct diagnosis rate was 72 days.
Conclusions: Considering the state of oral mucositis, receiving FDG-PET after SSIACRT is appropriate at approximately 3 months; however, when oral mucositis is sufficiently improved, FDG-PET should be performed earlier. |
|
言語 |
en |
| 書誌情報 |
en : Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
巻 34,
号 3,
p. 287-293,
発行日 2022-05
|
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2212-5566 |
| item_1735020952570 |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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|
関連識別子 |
https://doi.org/10.1016/j.ajoms.2021.10.018 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
© 2021 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI. Published by Elsevier Ltd. All rights reserved. |
| 出版タイプ |
|
|
出版タイプ |
NA |
|
出版タイプResource |
http://purl.org/coar/version/c_be7fb7dd8ff6fe43 |
| 出版者 |
|
|
出版者 |
Elsevier |
|
言語 |
en |
| 関連情報 |
|
|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
URI |
|
|
関連識別子 |
https://www.sciencedirect.com/science/article/pii/S2212555821002167?via%3Dihub |
