WEKO3
アイテム
Predictive symptoms associated with the development of radiographic knee osteoarthritis: a 10-year longitudinal study from the Iwaki cohort
http://hdl.handle.net/10129/0002000927
http://hdl.handle.net/10129/0002000927ab033ab6-8445-4b6c-8091-eff14a29901e
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| Item type | リポジトリ登録用アイテムタイプ（シンプル）(1) | |||||||||
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| 公開日 | 2025-06-13 | |||||||||
| タイトル | ||||||||||
| タイトル | Predictive symptoms associated with the development of radiographic knee osteoarthritis: a 10-year longitudinal study from the Iwaki cohort | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Knee osteoarthritis | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Development | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | General population | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Symptoms | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Prediction | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Cohort | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子（シンプル） | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ（シンプル） | doctoral thesis | |||||||||
| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 著者 |
佐藤, 英太郎
× 佐藤, 英太郎
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| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Purpose: This 10-year longitudinal cohort study aimed to investigate the annual rate of development of radiographic knee osteoarthritis (drKOA) and its predictive symptoms in the general Japanese population. Methods: A total of 263 volunteers (154 women) from the Iwaki Health Promotion Project were followed up over 10 years. Standing anteroposterior knee radiographs were obtained and the Kellgren–Lawrence grade was evaluated. drKOA was defined as a change from grade 0 or 1 to 2 over 10 years. Knee symptoms were evaluated using the Knee injury and Osteoarthritis Outcome Score at baseline. Logistic regression analyses were performed to identify symptoms related to drKOA, and a predictive formula was created based on the associated symptoms. Results: The overall incidence of drKOA was 52.9% (annual rate, 4.34%). Regression analysis revealed that predictive symptoms for drKOA were stiffness [p ¼ 0.033; odds ratio (OR) ¼ 1.89], frequent pain (p ¼ 0.024; OR ¼ 1.38), difficulty in ascending stairs, jumping, twisting, and kneeling (p ¼ 0.009–0.046; OR ¼ 1.71–2.78), and poor knee-related quality of life (p < 0.001–0.005; OR ¼ 1.53–2.18). Furthermore, the prediction formula created using these predictive symptoms demonstrated an area under the curve of 0.663, a cutoff value of 97 out of 100 points, an OR of 2.99, p < 0.001, sensitivity of 0.676, and specificity of 0.589. Conclusions: The annual incidence rate of drKOA was 4.34% in the general Japanese population. The identified symptoms would be useful to predict the drKOA and consider the etiology of the early phase of this disease. |
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| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Author: Eitaro Sato , Eiji Sasaki , Daisuke Chiba , Takahiro Tsushima , Yuka Kimura ,Yukiko Sakamoto , Yoshiko Takahashi , Mizuri Ishida , Eiichi Tsuda , Yasuyuki Ishibashi | |||||||||
| 言語 | en | |||||||||
| 書誌情報 |
en : Journal of Joint Surgery and Research 巻 3, 号 1, p. 35-41 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | EISSN | |||||||||
| 収録物識別子 | 2949-7051 | |||||||||
| DOI | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | https://doi.org/10.1016/j.jjoisr.2024.12.002 | |||||||||
| 権利情報 | ||||||||||
| 言語 | en | |||||||||
| 権利情報 | © 2024 The Author(s). Published by Elsevier B.V. on behalf of The Japanese Hip Society, The Japanese Society for Replacement Arthroplasty and The Japanese Knee Society. | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 出版者 | ||||||||||
| 出版者 | ELSEVIER | |||||||||
| 言語 | en | |||||||||
| 学位名 | ||||||||||
| 言語 | ja | |||||||||
| 学位名 | 博士（医学） | |||||||||
| 学位授与機関 | ||||||||||
| 言語 | ja | |||||||||
| 学位授与機関名 | 弘前大学 | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2025-03-24 | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第2311号 | |||||||||
