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＜Symposium V＞Novel rat middle cerebral artery occlusion model : Trans-femoral artery approach combined with preservation of the external carotid artery
http://hdl.handle.net/10129/3680
http://hdl.handle.net/10129/36809ae5785c-9b2b-4e1d-a80f-55bc8e0febf5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HirosakiMedJ_61_S142.pdf (299.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2010-08-18 | |||||||||
| タイトル | ||||||||||
| タイトル | ＜Symposium V＞Novel rat middle cerebral artery occlusion model : Trans-femoral artery approach combined with preservation of the external carotid artery | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Cerebral ischemia | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | micro guide wire | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | neurological evaluation | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | rat | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | trans-femoral artery approach | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Shimamura, Norihito
× Shimamura, Norihito
× Ohkuma, Hiroki
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| 著者(ヨミ) | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 12508 | |||||||||
| 姓名 | シマムラ, ノリヒト | |||||||||
| 著者(ヨミ) | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 12509 | |||||||||
| 姓名 | オオクマ, ヒロキ | |||||||||
| 著者別名 | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 12510 | |||||||||
| 識別子Scheme | 研究者総覧 | |||||||||
| 識別子URI | http://hue2.jm.hirosaki-u.ac.jp/html/298_ja.html | |||||||||
| 識別子 | 298 | |||||||||
| 姓名 | 嶋村, 則人 | |||||||||
| 著者別名 | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 12511 | |||||||||
| 姓名 | 大熊, 洋揮 | |||||||||
| 著者所属 | ||||||||||
| Department of Neurosurgery, Hirosaki University School of Medicine | ||||||||||
| 著者所属 | ||||||||||
| Department of Neurosurgery, Hirosaki University School of Medicine | ||||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | We developed a novel trans-femoral artery approach to the rat middle cerebral artery occlusion model （TF-MCAO） without sacrifi cing the external carotid artery （ECA） with/without the pterygopalatine artery, which is important for chewing food. To make the TF-MCAO we fi rst dissect the left common carotid artery（ CCA）, ECA, and internal carotid artery（ ICA）. Transient occlusion clips are applied to the proximal ECA and the pterygopalatine artery; we never sacrifi ce the ECA branch. A 24-gage catheter is inserted into the left femoral artery. We insert a slightly bent 0.014 inch hydrophilically-coated guide wire via a haemostasis valve. Anatomically, the left common carotid artery is located rostral to the descending aorta, permitting a straight-forward, blind approach to the CCA. The guide wire is gently advanced about 17 mm from the bifurcation of the CCA until slight resistance is encountered. The guide wire and temporary occlusion clips are withdrawn after 90 minutes. Rats were sacrifi ced 24h after reperfusion. Eleven rats were examined. One rat died before occlusion due to deep anesthesia. The success rate for producing infarction was 80%. The mean infarction volume of the basal ganglia was 94.4 ㎣ ± 9.4 se and mean infarction volume of the cerebral cortex was 124.2 ㎣ ± 21.6 se. No rat died due to cerebral infarction and no rat suff ered subarachnoid hemorrhage. We conclude that TF-MCAO was useful for producing a cerebral infarction. | |||||||||
| 引用 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 弘前医学. 61(Suppl.), 2010, p.S142-S146 | |||||||||
| 書誌情報 |
弘前医学 巻 61, 号 Supplement, p. S142-S146, 発行日 2010-07-08 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0439-1721 | |||||||||
| 書誌レコードID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AN00211444 | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 日本十進分類法 | ||||||||||
| 主題Scheme | NDC | |||||||||
| 主題 | 490 | |||||||||
| NIIサブジェクト | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 医学 | |||||||||
| 出版者 | ||||||||||
| 出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||||||
| 資源タイプ | ||||||||||
| 値 | Article | |||||||||
