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Lessons Learned after Twenty Years of Pancreas Transplantation at UCSF
http://hdl.handle.net/10129/4862
http://hdl.handle.net/10129/4862f92c36f2-5fad-4f1b-a4cd-6289df7c957d
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HirosakiMedJ_64_S9.pdf (297.6 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2013-04-30 | |||||||
| タイトル | ||||||||
| タイトル | Lessons Learned after Twenty Years of Pancreas Transplantation at UCSF | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | Pancreas Transplant | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | Kidney Transplant | |||||||
| キーワード | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | mmunosuppression | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
Freise, Chris E.
× Freise, Chris E.
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| 著者所属 | ||||||||
| 値 | Professor of Surgery UCSF, San Francisco, CA, USA | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | The University of California at San Francisco （UCSF）, initiated a pancreas transplant program in 1989. Since that time, nearly 500 procedures have been performed, with the majority being simultaneous pancreas kidney transplants（ SPK）. More recently, pancreas after previous kidney transplant（ PAK）, as well as pancreas transplant alone（ PTA）, have been performed in greater numbers. The procedure has been modified over time, with all cases now having systemic venous drainage, and exocrine drainage into the distal small bowel. Immunosuppression has changed as well, with all patients now receiving thymoglobulin induction, tacrolimus and mycophenolate mofetil maintenance, and prednisone with sirolimus in the PTA and PAK patients, as well as the highly sensitized SPK patients. However, low immunologic risk SPK patients are routinely managed with a steroid free maintenance protocol with excellent short and long term results, as well as rejection rates under 10%. Prophylaxis against immunosuppression related infections has also been an important part of the success, and more recently careful monitoring for polyoma infection has improved outcomes as well. Graft and patient survival for SPK and PTA/PAK continue to be excellent, and this review will discuss the evolution of our program over the last twenty years, reviewing the current approaches that have resulted in this success. | |||||||
| 引用 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 弘前医学. 64(Suppl.), 2013, p.S9-S18 | |||||||
| 書誌情報 |
弘前医学 巻 64, 号 Supplement, p. S9-S18, 発行日 2013-04-02 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 0439-1721 | |||||||
| 書誌レコードID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN00211444 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
| 日本十進分類法 | ||||||||
| 主題Scheme | NDC | |||||||
| 主題 | 490 | |||||||
| NIIサブジェクト | ||||||||
| 主題Scheme | Other | |||||||
| 主題 | 医学 | |||||||
| 出版者 | ||||||||
| 出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||||
| 資源タイプ | ||||||||
| 値 | Article | |||||||
