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A Morphometric Investigation of Pulmonary Sympathetic Innervation in Nitrofen-Induced Congenital Diaphragmatic Hernia Rats
http://hdl.handle.net/10129/5317
http://hdl.handle.net/10129/531792642254-43aa-465a-8ee3-1a1497d54e99
名前 / ファイル | ライセンス | アクション |
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HirosakiMedJ_65(1)_74.pdf (1.0 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-05-22 | |||||
タイトル | ||||||
タイトル | A Morphometric Investigation of Pulmonary Sympathetic Innervation in Nitrofen-Induced Congenital Diaphragmatic Hernia Rats | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | congenital diaphragmatic hernia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pulmonary hypoplasia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | autonomic innervation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 先天性横隔膜ヘルニア | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 肺低形成 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 自律神経支配 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kobayashi, Tamotsu
× Kobayashi, Tamotsu× Sugai, Michihiro× Mori, Fumiaki× Wakabayashi, Koichi× Hakamada, Kenichi |
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著者(ヨミ) | ||||||
姓名 | コバヤシ, タモツ | |||||
著者(ヨミ) | ||||||
姓名 | スガイ, ミチヒロ | |||||
著者(ヨミ) | ||||||
姓名 | モリ, フミアキ | |||||
著者(ヨミ) | ||||||
姓名 | ワカバヤシ, コウイチ | |||||
著者(ヨミ) | ||||||
姓名 | ハカマダ, ケンイチ | |||||
著者別名 | ||||||
姓名 | 小林, 完 | |||||
著者別名 | ||||||
姓名 | 須貝, 道博 | |||||
著者別名 | ||||||
姓名 | 森, 文秋 | |||||
著者別名 | ||||||
姓名 | 若林, 孝一 | |||||
著者別名 | ||||||
姓名 | 袴田, 健一 | |||||
著者所属 | ||||||
Department of Pediatric Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pediatric Surgery, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Neuropathology, Institute of Brain Science, Hirosaki University Graduate School of Medicine | ||||||
著者所属 | ||||||
Department of Pediatric Surgery, Hirosaki University Graduate School of Medicine | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | ulmonary hypoplasia influences prognosis in congenital diaphragmatic hernia (CDH). However, the abnormality of pulmonary innervation is not clearly understood. We immunohistochemically examined the lungs of CDH model rats, with special reference to sympathetic innervation. Pregnant rats were received nitrofen on gestational day 9 and the fetuses were recovered on gestational day 22. Control animals received only olive oil. Fetal lungs were dissected and the weight was measured. Whole mount sections at the level of main bronchus were immunostained using anti-tyrosine hydroxylase (TH) antibody as a sympathetic marker. The proportion of area of TH-immunoreactive nerve fi bers relative to the total lung area was calculated. The mean lung weight of CDH aff ected side was signifi cantly lower than that of ipsilateral side of controls. The percentage of TH-positive area of CDH affected side was significantly lower than that of unaffected side. The reduction of pulmonary sympathetic innervation may play an important role in respiratory morbidity in CDH. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 弘前医学. 65, 2014, p.74-81 | |||||
書誌情報 |
弘前医学 巻 65, 号 1, p. 74-81, 発行日 2014-04-15 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 493.3 | |||||
その他のタイトル | ||||||
その他のタイトル | Nitrofen 誘発先天性横隔膜ヘルニアラットにおける肺の交感神経支配に関する定量形態学的検討 | |||||
タイトル(ヨミ) | ||||||
その他のタイトル | Nitrofen ユウハツ センテンセイ オウカクマク ヘルニア ラット ニオケル ハイ ノ コウカン シンケイ シハイ ニカンスル テイリョウ ケイタイガク テキ ケントウ | |||||
NIIサブジェクト | ||||||
主題Scheme | Other | |||||
主題 | 医学 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||
資源タイプ | ||||||
値 | Article |