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  1. 30 医学部・医学研究科・保健学研究科
  2. 30a 学術雑誌論文
  3. 1.学術雑誌論文

Spontaneous regression of anterior mediastinal seminoma with normalization of beta-human chorionic gonadotropin levels

http://hdl.handle.net/10129/00006538
http://hdl.handle.net/10129/00006538
232ffdc3-1ea9-4708-b13e-9cab9e2ef895
名前 / ファイル ライセンス アクション
1-s2.0-S2210261217304157-main.pdf 1-s2.0-S2210261217304157-main (1.2 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2019-03-08
タイトル
タイトル Spontaneous regression of anterior mediastinal seminoma with normalization of beta-human chorionic gonadotropin levels
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Yu, Zaiqiang

× Yu, Zaiqiang

Yu, Zaiqiang

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Kimura, Daisuke

× Kimura, Daisuke

Kimura, Daisuke

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Tsushima, Takao

× Tsushima, Takao

Tsushima, Takao

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Fukuda, Ikuo

× Fukuda, Ikuo

Fukuda, Ikuo

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著者所属
値 Hirosaki Univ, Grad Sch Med, Dept Thorac & Cardiovasc Surg
抄録
内容記述タイプ Abstract
内容記述 INTRODUCTION: Although spontaneous regression (SR) of anterior mediastinal seminoma is very rare with normalization of p-human chorionic gonadotropin (beta-hCG) level, video-assisted thoracic surgery (VATS) is the most effective solution for definite diagnosis of indeterminate anterior mediastinal masses.

DIAGNOSIS, THERAPEUTIC INTERVENTIONS, AND OUTCOMES: A rare case of an asymptomatic 37-year-old man with an anterior mediastinal mass that was detected on a routine chest X-ray is presented. Computed tomography (CT) showed a large anterior mediastinal tumor with superior vena cava invasion and SR before VATS for definitive diagnosis. On pathology, the definitive diagnosis was seminoma. Microscopic examination showed abundant apoptotic cells within the tumor. Chemotherapy (bleomycin 30 mg/day, etoposide 200 mg/day, cisplatin 40 mg/day) was given to this patient, and the tumor showed high sensitivity.

CONCLUSION: Anterior mediastinal seminoma showing SR induced by spontaneous apoptosis of tumor cells may have good sensitivity to chemotherapy, and a good clinical outcome may be achieved in these patients. This case also highlights that VATS is the most effective solution for definite diagnosis of indeterminate anterior mediastinal masses. (C) 2017 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.
書誌情報 INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS

巻 39, p. 199-202, 発行日 2017
ISSN
収録物識別子タイプ ISSN
収録物識別子 2210-2612
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.1016/j.ijscr.2017.08.024
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
資源タイプ
値 Article
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