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Spontaneous regression of anterior mediastinal seminoma with normalization of beta-human chorionic gonadotropin levels
http://hdl.handle.net/10129/00006538
http://hdl.handle.net/10129/00006538232ffdc3-1ea9-4708-b13e-9cab9e2ef895
| 名前 / ファイル | ライセンス | アクション |
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1-s2.0-S2210261217304157-main (1.2 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| 公開日 | 2019-03-08 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Spontaneous regression of anterior mediastinal seminoma with normalization of beta-human chorionic gonadotropin levels | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 著者 |
Yu, Zaiqiang
× Yu, Zaiqiang
× Kimura, Daisuke
× Tsushima, Takao
× Fukuda, Ikuo
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| 著者所属 | ||||||||||||||
| Hirosaki Univ, Grad Sch Med, Dept Thorac & Cardiovasc Surg | ||||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | INTRODUCTION: Although spontaneous regression (SR) of anterior mediastinal seminoma is very rare with normalization of p-human chorionic gonadotropin (beta-hCG) level, video-assisted thoracic surgery (VATS) is the most effective solution for definite diagnosis of indeterminate anterior mediastinal masses. DIAGNOSIS, THERAPEUTIC INTERVENTIONS, AND OUTCOMES: A rare case of an asymptomatic 37-year-old man with an anterior mediastinal mass that was detected on a routine chest X-ray is presented. Computed tomography (CT) showed a large anterior mediastinal tumor with superior vena cava invasion and SR before VATS for definitive diagnosis. On pathology, the definitive diagnosis was seminoma. Microscopic examination showed abundant apoptotic cells within the tumor. Chemotherapy (bleomycin 30 mg/day, etoposide 200 mg/day, cisplatin 40 mg/day) was given to this patient, and the tumor showed high sensitivity. CONCLUSION: Anterior mediastinal seminoma showing SR induced by spontaneous apoptosis of tumor cells may have good sensitivity to chemotherapy, and a good clinical outcome may be achieved in these patients. This case also highlights that VATS is the most effective solution for definite diagnosis of indeterminate anterior mediastinal masses. (C) 2017 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. |
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| 書誌情報 |
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS 巻 39, p. 199-202, 発行日 2017 |
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| ISSN | ||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||
| 収録物識別子 | 2210-2612 | |||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | 10.1016/j.ijscr.2017.08.024 | |||||||||||||
| 著者版フラグ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
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| 値 | Article | |||||||||||||
