| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2019-03-11 |
| タイトル |
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タイトル |
Clinical relevance of aortic calcification in urolithiasis patients |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Tanaka, Toshikazu
Hatakeyama, Shingo
Yamamoto, Hayato
Narita, Takuma
Hamano, Itsuto
Matsumoto, Teppei
Soma, Osamu
Tobisawa, Yuki
Yoneyama, Tohru
Yoneyama, Takahiro
Hashimoto, Yasuhiro
Koie, Takuya
Takahashi, Ippei
Nakaji, Shigeyuki
Terayama, Yuriko
Funyu, Tomihisa
Ohyama, Chikara
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| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Adv Transplant & Regenerat Med |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Adv Transplant & Regenerat Med |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Sch Med, Dept Social Med |
| 著者所属 |
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Hirosaki Univ, Sch Med, Dept Social Med |
| 著者所属 |
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Oyokyo Kidney Res Inst, Dept Urol |
| 著者所属 |
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Oyokyo Kidney Res Inst, Dept Urol |
| 著者所属 |
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Hirosaki Univ, Grad Sch Med, Dept Urol |
| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Background: The aim of the present study is to investigate the clinical relevance of aortic calcification in urolithiasis patients.
Methods: Between January 2010 and September 2014, 1221 patients with urolithiasis were treated in Oyokyo Kidney Research Institute and Hirosaki University Hospital. Among these, 287 patients( Stone group) on whom adequate data were available were included in this retrospective study. We also selected 148 subjects with early stage( pT1N0M0) renal cell carcinoma from 607 renal cell carcinoma patients who underwent radical nephrectomy at Hirosaki University Hospital( Non-stone group) as control subjects. Validity of the Non-stone group was evaluated by comparison with pair-matched 296 volunteers from 1166 subjects who participated in the Iwaki Health Promotion Project in 2014. Thereafter, age, body mass index, aortic calcification index( ACI), renal function, serum uric acid concentrations, and comorbidities( diabetes, hypertension, or cardiovascular disease) were compared between the Non-stone and Stone groups. Independent factors for higher ACI and impaired renal function were assessed using multivariate logistic regression analysis.
Results: We confirmed relevance of Non-stone group patients as a control subject by comparing the pairmatched community-dwelling volunteers. Backgrounds of patients between the Non-stone and Stone groups were not significantly different except for the presence of hypertension in the Stone group. ACI was not significantly high in the Stone group compared with the Non-stone group. However, age-adjusted ACI was greater in the Stone group than the Non-stone group. Among urolithiasis patients, ACI was significantly higher in uric acid containing stone patients. The number of patients with stage 3B chronic kidney disease( CKD) was significantly higher in the Stone group than in the Non-stone group( 12% vs. 4%, P = 0.008). Multivariate logistic regression analysis showed higher aortic calcification index(>13%), and being a stone former were independent factors for stage 3B CKD at the time of diagnosis.
Conclusion: Aortic calcification and being a stone former had harmful influence on renal function |
| 書誌情報 |
BMC UROLOGY
巻 17,
p. 25,
発行日 2017-04-04
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| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1471-2490 |
| DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.1186/s12894-017-0218-2 |
| 著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 資源タイプ |
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値 |
Article |
s12894-017-0218-2 (860.3 kB)
