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Effect of Anesthetic Induction with Propofol Versus Thiopental on Outcomes of Newborns and Women Undergoing Cesarean Section : A Propensity Score Matching analysis
http://hdl.handle.net/10129/00006593
http://hdl.handle.net/10129/0000659378464fb6-bad8-410c-b910-ccfb1c586cb4
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HirosakiMedJ_69(1-4)_155.pdf (169.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2019-04-10 | |||||
| タイトル | ||||||
| タイトル | Effect of Anesthetic Induction with Propofol Versus Thiopental on Outcomes of Newborns and Women Undergoing Cesarean Section : A Propensity Score Matching analysis | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cesarean section | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | general anesthesia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | propofol | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | thiopental | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | fetus | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Ota, Daichi
× Ota, Daichi× Kudo, Tomoyuki× Kawaguchi, Jun× Niwa, Hidetomo× Hirota, Kazuyoshi |
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| 著者所属 | ||||||
| 値 | Department of Anesthesiology, Hirosaki University Hospital | |||||
| 著者所属 | ||||||
| 値 | Department of Anesthesiology, Hirosaki University Hospital | |||||
| 著者所属 | ||||||
| 値 | Department of Anesthesiology, Hirosaki University Hospital | |||||
| 著者所属 | ||||||
| 値 | Department of Anesthesiology, Hirosaki University Hospital | |||||
| 著者所属 | ||||||
| 値 | Department of Anesthesiology, Hirosaki University Graduate School of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: We conducted a single-center retrospective study with propensity score matching to clarify which anesthetic agent, i.e., thiopental or propofol, provides better outcomes for newborns and women undergoing elective and/or urgent cesarean section with general anesthesia. Methods: We collected maternal and fetal data（ n=935） using obstetric and anesthetic charts of cesarean sections with general anesthesia between 1994 and 2013. After 1:1 propensity score matching with maternal age, body mass index,gestational period, fetal weight, type of surgery, pre-eclampsia, and fetal/maternal indication, we compared thiopental to propofol （n=392） regarding the following outcomes. The fetal primary outcome was their well-being evaluated by Apgar score （APS）. The maternal primary outcome was the patient's hemodynamic changes due to tracheal intubation or delivery. Results: The only APS at 1 min was significantly higher in the thiopental group. The other fetal outcomes such as APS at 5 minutes, the umbilical cord blood pH, and proportion of neonatal asphyxia after birth were similar between two groups. Regarding maternal outcomes, propofol significantly suppressed the increase in the patients' blood pressure from anesthetic induction to the delivery. Conclusions: Our results indicate that propofol induction may be a first choice for cesarean section with general anesthesia. |
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| 書誌情報 |
弘前医学 巻 69, 号 1-4, p. 155-162, 発行日 2019-03-15 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0439-1721 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00211444 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 日本十進分類法 | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| 出版者 | ||||||
| 出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||
