| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2020-03-06 |
| タイトル |
|
|
タイトル |
Establishment of cardiac action potential recording using a membrane potential indicator in the mouse sinoatrial node |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Channel |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
calcium |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
heart rate |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
mouse |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
fluorescence |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Toyama, Yuichi
Yonekura, Manabu
Arakawa, Yoshiaki
Higuchi, Shoki
Tomita, Hirofumi
Murakami, Agnieszka
Itagaki, Shirou
Murakami, Manabu
|
| 著者所属 |
|
|
|
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
|
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
|
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
|
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
|
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
|
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
|
Collaboration Center for Community and Industry Sapporo Medical University |
| 著者所属 |
|
|
|
Department of Pharmacology, Hirosaki University Graduate School of Medicine |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The cardiac action potential in the sinoatrial node is important, as it propagates throughout the heart and determines cardiac rhythm. Because of the anatomical complexity, pacemaker cells in the sinoatrial node can be difficult to identify for ectrophysiological analysis. Also, analysis of pacemaker cells requires a specialized technique. In this study, we tried to analyze pacemaking in the sinoatrial node. First, we evaluated the expression of various factors that participate in pacemaking or modify cardiac rhythm. Next, we evaluated recordings of the action potential in the sinoatrial node by a conventional lectrophysiological technique and using oxonol V, a fluorescent voltage-sensitive dye. |
| 書誌情報 |
弘前医学
巻 70,
号 2-4,
p. 163-171,
発行日 2020-03-02
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0439-1721 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN00211444 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
弘前大学大学院医学研究科 |
Hirosaki Med J 70-2-4_163 (993.2 kB)
