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Congenital Anomalies in the Offspring of Epileptic Mothers
http://hdl.handle.net/10129/2037
http://hdl.handle.net/10129/20371dba3d29-2442-431f-ae1e-501cea136d60
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
CongAnom_32_309.pdf (749.8 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2009-07-17 | |||||||||
| タイトル | ||||||||||
| タイトル | Congenital Anomalies in the Offspring of Epileptic Mothers | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | epilepys | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | malformation | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | congenital anomaly | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | pregnancy | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | antiepileptic drug | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | facial cleft | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Nakane, Yoshibumi
× Nakane, Yoshibumi
× Kaneko, Sunao
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| 著者(ヨミ) | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 9611 | |||||||||
| 姓名 | ナカネ, ヨシブミ | |||||||||
| 著者(ヨミ) | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 9355 | |||||||||
| 姓名 | カネコ, スナオ | |||||||||
| 著者別名 | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 9613 | |||||||||
| 姓名 | 中根, 充文 | |||||||||
| 著者別名 | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 9351 | |||||||||
| 姓名 | 兼子, 直 | |||||||||
| 著者所属 | ||||||||||
| 値 | Department of Neuropsychiatry, Nagasaki University School of Medicine | |||||||||
| 著者所属 | ||||||||||
| 値 | Department of Neuropsychiatry, Hirosaki University School of Medicine | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | The incidences of various complications during pregnancy are not significantly different between epileptic and nonepileptic mothers in the majority of papers so far reported. More than 70 to 80010 of women with epilepsy will have no change in seizure frequency, while 5010 will have fewer seizures than before and the remaining patients will have more seizures during pregnancy provided that their drug compliance is good. Intrauterine growth, in particular, of head circumference of fetus is delayed. However, this retardation disappears within few years after birth. The risk of congenital malformations of the offspring born to treated epileptic mothers is greater than in the general population. Among risk factors for teratogenesis that had been considered to date, only antiepileptic drug (AED)-related factors had proved to be significantly related to the occurrence of malformations. Among AEDs, methylphenobarbital, valproate, primidone, carbamazepine and phenytoin are teratogenic, particularly when they are used in combination. Follow up EEG of children born to epileptic mothers revealed that the incidence of abnormal EEG was 44010, and 28 to 38010 showed epileptiform patterns. Only 7010 of offspring had epileptic seizures. In the offspring without clinical seizures revealed that most of the epileptiform patterns disappear after the age 10. Recommendations concerning AED therapy during pregnancy are also discussed. |
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| 引用 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Congenital Anomalies. 32(4), 1992, p.309-321 | |||||||||
| 書誌情報 |
Congenital Anomalies 巻 32, 号 4, p. 309-321, 発行日 1992-12-30 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0914-3505 | |||||||||
| 書誌レコードID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AN10066760 | |||||||||
| 権利 | ||||||||||
| 権利情報 | 日本先天異常学会 | |||||||||
| 権利 | ||||||||||
| 権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||||||
| フォーマット | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | application/pdf | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 日本十進分類法 | ||||||||||
| 主題Scheme | NDC | |||||||||
| 主題 | 493.7 | |||||||||
| NIIサブジェクト | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 内科系臨床医学 | |||||||||
| 出版者 | ||||||||||
| 出版者 | 日本先天異常学会 | |||||||||
| 資源タイプ | ||||||||||
| 値 | Article | |||||||||
| 異版である | ||||||||||
| 関連タイプ | isVersionOf | |||||||||
| 識別子タイプ | URI | |||||||||
| 関連識別子 | http://ci.nii.ac.jp/naid/110002786721 | |||||||||
