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Combined utility of maximum standardized uptake value and its change after neoadjuvant chemotherapy in predicting postoperative recurrence in esophageal cancer
http://hdl.handle.net/10129/00008201
http://hdl.handle.net/10129/0000820151f7ba51-d223-4bb3-a901-720ec9e9d344
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Hirosaki Med J 73-1-4_54 (1.6 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2023-04-24 | |||||
| タイトル | ||||||
| タイトル | Combined utility of maximum standardized uptake value and its change after neoadjuvant chemotherapy in predicting postoperative recurrence in esophageal cancer | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | esophageal cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | fluorodeoxyglucose positron emission tomography | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | standardised uptake value | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | prognostic factor | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | neoadjuvant therapy | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Saito, Kensuke
× Saito, Kensuke× Yoshizawa, Tadashi× Morohashi, Satoko× Seino, Hiroko× Goto, Shintaro× Muroya, Takahiro× Yokoyama, Hiroshi× Yoshida, Eri× Miura, Hiroyuki× Yu, Chen× Kijima, Hiroshi× Kakeda, Shingo× Hakamada, Kenichi× Sato, Atsushi |
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| 著者所属 | ||||||
| 値 | Department of Medical Oncology, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Radiology, Aomori National Hospital | |||||
| 著者所属 | ||||||
| 値 | Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Radiology, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Medical Oncology, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Radiology, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine | |||||
| 著者所属 | ||||||
| 値 | Department of Medical Oncology, Hirosaki University Graduate School of Medicine | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Positron emission tomography（PET） is the standard method for metabolic and quantitative evaluation of therapeutic response to chemotherapy in solid tumors. This study determined the ability of PET parameters used in combination in predicting recurrence-free survival（RFS）after neoadjuvant chemotherapy （NAC）and operation for esophageal cancer. Methods: This single-center retrospective study included 96 patients who underwent 18F-fluorodeoxyglucose-PET/computed tomography before and after NAC. Maximum standardised uptake value（SUVmax）after NAC and the rate of change in SUVmax following NAC（ΔSUVmax）were determined to examine their relationship with postoperative recurrence and clinicopathological factors. Results: Receiver operating characteristic curves, with recurrence after NAC as the event, were used to determine optimal cut-off SUVmax and ΔSUVmax of 6.8 and 45.7, respectively. Using these cut-off values, the patients were classified into four groups: Group A, SUVmax > 6.8 and ΔSUVmax ≤ 45.7; Group B, SUVmax > 6.8 and ΔSUVmax > 45.7; Group C, SUVmax ≤ 6.8 and ΔSUVmax ≤ 45.7; and Group D, SUVmax ≤ 6.8 and ΔSUVmax > 45.7. Of the four groups, Group D had the longest RFS compared to the other groups. Conclusion: Combination of SUVmax with ΔSUVmax was useful for evaluating the effects of NAC in patients with esophageal cancer. |
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| 書誌情報 |
弘前医学 en : Hirosaki Medical Journal 巻 73, 号 1-4, p. 54-66, 発行日 2023-03-22 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0439-1721 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00211444 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 弘前大学大学院医学研究科 | |||||
| 資源タイプ | ||||||
| 値 | Article | |||||
