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アイテム
Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo
http://hdl.handle.net/10129/4859
http://hdl.handle.net/10129/4859e5ec8c1f-3ec7-4e5e-866a-24fba91efbf1
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
HirosakiMedJ_64_S1.pdf (329.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2013-04-30 | |||||||||
| タイトル | ||||||||||
| タイトル | Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | mesenchymal stem cell | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | high mobility group box 1 | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | epidermolysis bullosa | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Tamai, Katsuto
× Tamai, Katsuto
× Kaneda, Yasufumi
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| 著者(ヨミ) | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 11519 | |||||||||
| 姓名 | タマイ, カツト | |||||||||
| 著者(ヨミ) | ||||||||||
| 識別子Scheme | WEKO | |||||||||
| 識別子 | 13727 | |||||||||
| 姓名 | カネダ, ヤスフミ | |||||||||
| 著者所属 | ||||||||||
| 値 | Department of Stem Cell Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University | |||||||||
| 著者所属 | ||||||||||
| 値 | Gene Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | group box 1 （HMGB1）, which mobilizes a sub-population of non-hematopoietic cells from bone marrow into the circulation to repair skin and restore Col 7 expression. These bone marrow-derived epithelial stem/progenitor cells are derived from a lineage-negative, platelet-derived growth factor alpha-positive mesenchymal stem cell pool in bone marrow, which represents less than 0.3% of the total bone marrow cell population. In addition, systemic administration of HMGB1 to wounded wild-type mice leads to faster wound healing with recruitment of these bone marrow cells to the wounded skin. This study identifies a suitable cell population for cell therapy approaches in individuals with RDEB, but also has broader implications for clinical medicine in identifying a means of mobilizing and recruiting a key population of bone marrow cells germane to tissue repair. | |||||||||
| 引用 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 弘前医学. 64(Suppl.), 2013, p.S1-S5 | |||||||||
| 書誌情報 |
弘前医学 巻 64, 号 Supplement, p. S1-S5, 発行日 2013-04-02 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 0439-1721 | |||||||||
| 書誌レコードID | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AN00211444 | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| 日本十進分類法 | ||||||||||
| 主題Scheme | NDC | |||||||||
| 主題 | 490 | |||||||||
| NIIサブジェクト | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 医学 | |||||||||
| 出版者 | ||||||||||
| 出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||||||
| 資源タイプ | ||||||||||
| 値 | Article | |||||||||
