WEKO3
アイテム
{"_buckets": {"deposit": "16345e50-e586-4c1e-854d-5ee3468ffc46"}, "_deposit": {"created_by": 3, "id": "3770", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "3770"}, "status": "published"}, "_oai": {"id": "oai:hirosaki.repo.nii.ac.jp:00003770", "sets": ["654"]}, "author_link": ["13725", "11519", "11514", "13727"], "item_3_biblio_info_8": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2013-04-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "Supplement", "bibliographicPageEnd": "S5", "bibliographicPageStart": "S1", "bibliographicVolumeNumber": "64", "bibliographic_titles": [{"bibliographic_title": "弘前医学"}]}]}, "item_3_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "group box 1 (HMGB1), which mobilizes a sub-population of non-hematopoietic cells from bone marrow into the circulation to repair skin and restore Col 7 expression. These bone marrow-derived epithelial stem/progenitor cells are derived from a lineage-negative, platelet-derived growth factor alpha-positive mesenchymal stem cell pool in bone marrow, which represents less than 0.3% of the total bone marrow cell population. In addition, systemic administration of HMGB1 to wounded wild-type mice leads to faster wound healing with recruitment of these bone marrow cells to the wounded skin. This study identifies a suitable cell population for cell therapy approaches in individuals with RDEB, but also has broader implications for clinical medicine in identifying a means of mobilizing and recruiting a key population of bone marrow cells germane to tissue repair.", "subitem_description_type": "Abstract"}]}, "item_3_description_7": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "弘前医学. 64(Suppl.), 2013, p.S1-S5", "subitem_description_type": "Other"}]}, "item_3_full_name_2": {"attribute_name": "著者(ヨミ)", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "11519", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "タマイ, カツト"}]}, {"nameIdentifiers": [{"nameIdentifier": "13727", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "カネダ, ヤスフミ"}]}]}, "item_3_publisher_35": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "弘前大学大学院医学研究科・弘前医学会"}]}, "item_3_radio_42": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_radio_item": "Article"}]}, "item_3_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00211444", "subitem_source_identifier_type": "NCID"}]}, "item_3_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0439-1721", "subitem_source_identifier_type": "ISSN"}]}, "item_3_subject_19": {"attribute_name": "日本十進分類法", "attribute_value_mlt": [{"subitem_subject": "490", "subitem_subject_scheme": "NDC"}]}, "item_3_subject_23": {"attribute_name": "NIIサブジェクト", "attribute_value_mlt": [{"subitem_subject": "医学", "subitem_subject_scheme": "Other"}]}, "item_3_text_4": {"attribute_name": "著者所属", "attribute_value_mlt": [{"subitem_text_value": "Department of Stem Cell Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University"}, {"subitem_text_value": "Gene Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University"}]}, "item_3_version_type_18": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tamai, Katsuto"}], "nameIdentifiers": [{"nameIdentifier": "11514", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kaneda, Yasufumi"}], "nameIdentifiers": [{"nameIdentifier": "13725", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-03-13"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "HirosakiMedJ_64_S1.pdf", "filesize": [{"value": "329.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 329700.0, "url": {"label": "HirosakiMedJ_64_S1.pdf", "url": "https://hirosaki.repo.nii.ac.jp/record/3770/files/HirosakiMedJ_64_S1.pdf"}, "version_id": "1c8737ec-d66f-487d-84ad-ad9081c6f497"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "mesenchymal stem cell", "subitem_subject_scheme": "Other"}, {"subitem_subject": "high mobility group box 1", "subitem_subject_scheme": "Other"}, {"subitem_subject": "epidermolysis bullosa", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo"}]}, "item_type_id": "3", "owner": "3", "path": ["654"], "permalink_uri": "http://hdl.handle.net/10129/4859", "pubdate": {"attribute_name": "公開日", "attribute_value": "2013-04-30"}, "publish_date": "2013-04-30", "publish_status": "0", "recid": "3770", "relation": {}, "relation_version_is_last": true, "title": ["Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo"], "weko_shared_id": 3}
Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo
http://hdl.handle.net/10129/4859
http://hdl.handle.net/10129/4859e5ec8c1f-3ec7-4e5e-866a-24fba91efbf1
名前 / ファイル | ライセンス | アクション |
---|---|---|
HirosakiMedJ_64_S1.pdf (329.7 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2013-04-30 | |||||
タイトル | ||||||
タイトル | Cross-talk between Bone Marrow and Tissue Injury : Novel Regenerative Therapy for Severely Damaged Tissues by Mobilizing Bone Marrow Mesenchymal Stem Cells in Vivo | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mesenchymal stem cell | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | high mobility group box 1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | epidermolysis bullosa | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tamai, Katsuto
× Tamai, Katsuto× Kaneda, Yasufumi |
|||||
著者(ヨミ) | ||||||
姓名 | タマイ, カツト | |||||
著者(ヨミ) | ||||||
姓名 | カネダ, ヤスフミ | |||||
著者所属 | ||||||
Department of Stem Cell Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University | ||||||
著者所属 | ||||||
Gene Therapy Science, Graduate School of Meicine, Graduate School of Medicine, Osaka University | ||||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | group box 1 (HMGB1), which mobilizes a sub-population of non-hematopoietic cells from bone marrow into the circulation to repair skin and restore Col 7 expression. These bone marrow-derived epithelial stem/progenitor cells are derived from a lineage-negative, platelet-derived growth factor alpha-positive mesenchymal stem cell pool in bone marrow, which represents less than 0.3% of the total bone marrow cell population. In addition, systemic administration of HMGB1 to wounded wild-type mice leads to faster wound healing with recruitment of these bone marrow cells to the wounded skin. This study identifies a suitable cell population for cell therapy approaches in individuals with RDEB, but also has broader implications for clinical medicine in identifying a means of mobilizing and recruiting a key population of bone marrow cells germane to tissue repair. | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 弘前医学. 64(Suppl.), 2013, p.S1-S5 | |||||
書誌情報 |
弘前医学 巻 64, 号 Supplement, p. S1-S5, 発行日 2013-04-02 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0439-1721 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00211444 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
日本十進分類法 | ||||||
主題Scheme | NDC | |||||
主題 | 490 | |||||
NIIサブジェクト | ||||||
主題Scheme | Other | |||||
主題 | 医学 | |||||
出版者 | ||||||
出版者 | 弘前大学大学院医学研究科・弘前医学会 | |||||
資源タイプ | ||||||
値 | Article |