| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2015-05-25 |
| タイトル |
|
|
タイトル |
MUC5AC-Negative Phenotype is Correlated with Poor Patient Prognosis of Pancreas Head Ductal Carcinoma. |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
mucin |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
MUC5AC |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
pancreas cancer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
bile duct cancer |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
patient prognosis |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Sakuraba, Shingo
Morohashi, Satoko
Yoshizawa, Tadashi
Tsutsumi, shinji
Kimura, Norihisa
Kudo, Daisuke
Ishido, Keinosuke
Toyoki, Yoshikazu
Hakamada, Kenichi
Kijima, Hiroshi
|
| 著者所属 |
|
|
値 |
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Department of Pathology and Bioscience, Hirosaki University Graduate School of Medicine |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Both pancreas head ductal carcinoma（ PHDC） and distal bile duct carcinoma（ DBDC） are located within the pancreas head/intra-pancreatic bile duct region, and are the most aggressive malignancies with poor patient prognosis. In the present study, we demonstrated clinicopathological features and patients prognosis of PHDC/DBDC. We examined total 87 surgically resected cases of PHDC （40 cases） and DBDC （47 cases）. PHDC showed frequent neural invasion （85.0%） and lymph node metastasis （77.5%）, compared with DBDC （57.4% and 40.4% respectively）, resulting in the poorer prognosis（ P=0.0219） than DBDC. In addition, PHDC expressed MUC2（ 10.0%）and MUC6 （25.0%） less frequently, compared with DBDC （36.2% and 55.3%, respectively）. MUC5AC-negative PHDC exhibited significantly poorer patient’s prognosis, compared with MUC5AC-positive PHDC （P=0.0111）, MUC5ACpositive DBDC （P=0.000162）, and MUC5AC-negative DBDC （P=0.00416）. In conclusion, MUC5AC-negative PHDC showed significantly poor patient’s prognosis. |
| 引用 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
弘前医学. 66, 2015, p.28-37 |
| 書誌情報 |
弘前医学
巻 66,
号 1,
p. 28-37,
発行日 2015-04-06
|
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0439-1721 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN00211444 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 日本十進分類法 |
|
|
主題Scheme |
NDC |
|
主題 |
490 |
| NIIサブジェクト |
|
|
主題Scheme |
Other |
|
主題 |
医学 |
| 出版者 |
|
|
出版者 |
弘前大学大学院医学研究科・弘前医学会 |
| 資源タイプ |
|
|
値 |
Article |
HirosakiMedJ_66(1)_28.pdf (1.3 MB)
